What is the NOAEL for N-[3-(Dimethylamino)propyl]octadecanamide?
N-[3-(Dimethylamino)propyl]octadecanamide has 6 NOAEL studies in the database. The lowest reported value is 1.7 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
N-[3-(Dimethylamino)propyl]octadecanamide
Also known as: Octadecanamide, N-[3-(dimethylamino)propyl]-, N,N-Dimethyl-3-octadecanoylaminopropylamine, N,N-Dimethyl-N-(3-stearamidopropyl)amine, EINECS 231-609-1, UNII-K7VEI00UFR
CAS 7651-02-7
N-[3-(Dimethylamino)propyl]octadecanamide (CAS 7651-02-7) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for stearamidopropyl-dimethylamine-safety →
Cross-Vertical Regulatory Divergence
N-[3-(Dimethylamino)propyl]octadecanamide is classified GHS Danger (H314, H315, H318, H400, H410, H411, H302, H317) in the chemicals database but is allowed in EU cosmetics at max 5%.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
N-[3-(Dimethylamino)propyl]octadecanamide
CAS Number
7651-02-7
DTXSID
DTXSID9064762
Molecular Formula
C23H48N2O
InChI Key
WWVIUVHFPSALDO-UHFFFAOYSA-N
Monoisotopic Mass
368.376664
Synonyms
Octadecanamide, N-[3-(dimethylamino)propyl]-N,N-Dimethyl-3-octadecanoylaminopropylamineN,N-Dimethyl-N-(3-stearamidopropyl)amineEINECS 231-609-1UNII-K7VEI00UFR
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Softener and conditionerSurfactant (surface active agent)Anti-static agentEmulsifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1.7 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| K7VEI00UFR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K7VEI00UFR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K7VEI00UFR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K7VEI00UFR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | N-[3-(dimethylamino)propyl]stearamide | 231-609-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
5%
Category
surfactant
Frequently Asked Questions
What regulatory lists include N-[3-(Dimethylamino)propyl]octadecanamide?
N-[3-(Dimethylamino)propyl]octadecanamide appears on 1 regulatory/inventory list including Europe; Personal care. Source: EPA CPDat.
Is N-[3-(Dimethylamino)propyl]octadecanamide used in cosmetics?
Yes, N-[3-(Dimethylamino)propyl]octadecanamide is also indexed as a cosmetic ingredient under the name stearamidopropyl-dimethylamine-safety. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N-[3-(Dimethylamino)propyl]octadecanamide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does N-[3-(Dimethylamino)propyl]octadecanamide have different safety status in cosmetics vs industrial chemicals?
N-[3-(Dimethylamino)propyl]octadecanamide is classified GHS Danger (H314, H315, H318, H400, H410, H411, H302, H317) in the chemicals database but is allowed in EU cosmetics at max 5%.
Is N-[3-(Dimethylamino)propyl]octadecanamide used outside industrial chemicals?
N-[3-(Dimethylamino)propyl]octadecanamide also appears in cosmetics databases.