What is the NOAEL for (+)-Cedrol?
(+)-Cedrol has 9 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP ICE skin sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
(+)-Cedrol
Also known as: 1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-,(3R,3aS,6R,7R,8aS)-, 8beta H-Cedran-8-ol, 1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-, [3R-(3α,3aβ,6α,7β,8aα)]-, α-Cedrol, Cedrol (+15 more)
CAS 77-53-2
(+)-Cedrol (CAS 77-53-2) is a chemical substance. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
9
SOURCE
Chemical inventory jurisdictions
Regulatory lists
10
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
(+)-Cedrol
CAS Number
77-53-2
Molecular Formula
C15H26O
InChI Key
SVURIXNDRWRAFU-OGMFBOKVSA-N
Monoisotopic Mass
222.198365
Synonyms
1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-,(3R,3aS,6R,7R,8aS)-8beta H-Cedran-8-ol1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-, [3R-(3α,3aβ,6α,7β,8aα)]-α-CedrolCedrol8βH-Cedran-8-ol3R,3aS,6R,7R,8aS)-Octahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-6-ol(3R,3AS,6R,7R,8aS)-3,6,8,8-tetramethyloctahydro-1H-3a,7-methanoazulen-6-olCedrol Nanomedicin(8α)-cedran-8-ol8-CEDROL[3R-(3α,3aβ,6α,7β,8aα)]-Octahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-6-ol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
58 records
Softener and conditionerDeodorizerNo specific technical functionFragranceHumectantFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
10 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Australia; Food and drug - smoking-related products | New Zealand ESR | CPCat |
| artificial_sweat; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| artificial_sweat; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| Cleaning products and household care - air freshener; Europe | Danish Environmental Protection Agency | Danish EPA |
| air; Cleaning products and household care - air freshener; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| consumer_product | P&G | Proctor & Gamble |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 5 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 4 | % | Concentration, one positive response | Dermal | Human | NTP ICE skin sensitization |
| 63ZM9703BO | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 8 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 5184 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 3240 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 2592 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP ICE skin sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | [3R-(3α,3aβ,6α,7β,8aα)]-octahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-6-ol | 201-035-6 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
terpene
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
CEDROL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include (+)-Cedrol?
(+)-Cedrol appears on 9 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Australia; Food and drug - smoking-related products, artificial_sweat; detected; emissions; Europe; Toys and children's products, and 6 more. Source: EPA CPDat.
Is (+)-Cedrol used in cosmetics?
Yes, (+)-Cedrol is also indexed as a cosmetic ingredient under the name Cedrol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (+)-Cedrol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is (+)-Cedrol used outside industrial chemicals?
(+)-Cedrol also appears in cosmetics, pharmaceutical, cannabis databases.