Also known as: Argenti nitras, Argerol, Caswell No. 737, EINECS 231-853-9, EPA Pesticide Chemical Code 072503 (+5 more)
CAS 7761-88-8
Silver nitrate (CAS 7761-88-8) is a chemical substance with GHS signal word Danger; key hazard signal: H272; H314; H400; H410. Key regulatory status: REACH registered, 27 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Silver nitrate is classified GHS Danger (H272, H314, H400, H410) in the chemicals database but is restricted in EU cosmetics at max 4%.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Ox. Sol. 2; Skin Corr. 1B; Aquatic Acute 1; Aquatic Chronic 1 | H272; H314; H400; H410 | GHS03; GHS05; GHS09 | Danger |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | May cause fire or explosion; strong oxidizer Harmful if swallowed Causes severe skin burns and eye damage Very toxic to aquatic life with long lasting effects |
| Short-term Effects | The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. |
| Long-term Effects | The substance may have effects on the blood. This may result in the formation of methaemoglobin. The substance may cause a grey-blue discolouration of the eyes and skin (argyria/argyrosis). Animal tests show that this substance possibly causes toxicity to human reproduction or development. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| Europe; Personal care; restricted | European Commission | CosIng |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.016 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 95IT3W8JZE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 95IT3W8JZE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 95IT3W8JZE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 95IT3W8JZE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | unitless | GHS Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| =6.47 | mg/org-day | LOEC | oral | Rat | ToxValDB_ECOTOX |
| =0.0093 | mmol/kg | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =0.75 | mg/kg bw/day | LOEL | injection | Mouse | ToxValDB_ECOTOX |
| =1.5 | mg/kg bw/day | LOEL | injection | Mouse | ToxValDB_ECOTOX |
| =2 | % | LOEL | injection | Mouse | ToxValDB_ECOTOX |
| =5 | mg/kg bw/day | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =65 | umol/kg/day | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =400 | mg/L | LOEL | oral | Mouse | ToxValDB_ECOTOX |
| =6.47 | mg/org-day | NOEC | oral | Rat | ToxValDB_ECOTOX |
| =0.183 | mg/kg bw/day | NOEL | injection | Rat | ToxValDB_ECOTOX |
| =1 | mg/kg bw/day | NOEL | injection | Mouse | ToxValDB_ECOTOX |
| =33 | umol/kg/day | NOEL | injection | Rat | ToxValDB_ECOTOX |
| 1.2 | % | Viability (240 minutes) | Dermal | - | NTP_ICE_skin_irritation |
| 6.4 | % | Viability (240 minutes) | Dermal | - | NTP_ICE_skin_irritation |
| 14.5 | % | Viability (240 minutes) | Dermal | - | NTP_ICE_skin_irritation |
| 12.1 | % | Viability (3 minutes) | Dermal | - | NTP_ICE_skin_irritation |
| 66.9 | % | Viability (3 minutes) | Dermal | - | NTP_ICE_skin_irritation |
| 80.6 | % | Viability (3 minutes) | Dermal | - | NTP_ICE_skin_irritation |
| 2.5 | % | Viability (60 minutes) | Dermal | - | NTP_ICE_skin_irritation |
| 4.4 | % | Viability (60 minutes) | Dermal | - | NTP_ICE_skin_irritation |
| 13.4 | % | Viability (60 minutes) | Dermal | - | NTP_ICE_skin_irritation |
Showing 27 of 27 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Silver nitrate | 231-853-9 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Silver nitrate (CAS 7761-88-8) is classified under EU CLP Annex VI as Ox. Sol. 2; Skin Corr. 1B; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H272; H314; H400; H410. Source: EU CLP Annex VI (ECHA).
Silver nitrate has 27 NOAEL studies in the database. The lowest reported value is 0.016 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
Silver nitrate appears on 6 regulatory/inventory lists including active_ingredient; Pesticides, active_ingredient; Europe; Pesticides, Indirect additives food contact (10/2018), and 3 more. Source: EPA CPDat.
Yes, Silver nitrate is also indexed as a cosmetic ingredient under the name Silver Nitrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Silver nitrate is classified GHS Danger (H272, H314, H400, H410) in the chemicals database but is restricted in EU cosmetics at max 4%.
Silver nitrate also appears in cosmetics, pharmaceutical databases.