What is the NOAEL for Ambrettolide?
Ambrettolide has 7 NOAEL studies in the database. The lowest reported value is S79ZK47L2P UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Ambrettolide
Also known as: Oxacycloheptadec-7-en-2-one, 16-Hydroxy-6-hexadecenoic acid lactone, 1-Oxa-7-cycloheptadecen-2-one, oxacycloheptadec-7-ene-2-one, Oxacycloheptadec-7-en-2-on (+9 more)
CAS 7779-50-2
Ambrettolide (CAS 7779-50-2) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
20 fields
Name
Ambrettolide
CAS Number
7779-50-2
DTXSID
DTXSID6040799
Molecular Formula
C16H28O2
InChI Key
HMWPDRYGIBLSHB-UHFFFAOYSA-N
Monoisotopic Mass
252.20893
Synonyms
Oxacycloheptadec-7-en-2-one16-Hydroxy-6-hexadecenoic acid lactone1-Oxa-7-cycloheptadecen-2-oneoxacycloheptadec-7-ene-2-oneOxacycloheptadec-7-en-2-onoxacicloheptadec-7-en-2-onaOxacycloheptadeca-7-en-2-oneCYCLOHEXADECEN-7-OLIDEEINECS 231-929-16-Hexadecenlactone, omega-6-Hexadecenolide16-Hydroxy-6-hexadecenoic acid omega-lactone
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| S79ZK47L2P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S79ZK47L2P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S79ZK47L2P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S79ZK47L2P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 648 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
Frequently Asked Questions
What regulatory lists include Ambrettolide?
Ambrettolide appears on 3 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Ambrettolide used in cosmetics?
Yes, Ambrettolide is also indexed as a cosmetic ingredient under the name Ambrettolide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ambrettolide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Ambrettolide used outside industrial chemicals?
Ambrettolide also appears in cosmetics databases.