NOAEL Data Cosmetic Ingredient

Nigrosine

Also known as: C.I. Acid Black 2, Acid Black 2, Calco nigrosine O 2P, CI Acid black 2, Lurazol Deep Blue EB (+3 more)

CAS 8005-03-6

Nigrosine (CAS 8005-03-6) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for CI 50420 →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 14 fields
Name
Nigrosine
CAS Number
8005-03-6
DTXSID
DTXSID1020934
Molecular Formula
C22H16N6O9S2.2Na
InChI Key
HKBVRFLHNUEVRO-HMDKGIQMSA-L
Monoisotopic Mass
618.021557
Synonyms
C.I. Acid Black 2Acid Black 2Calco nigrosine O 2PCI Acid black 2Lurazol Deep Blue EBNigrosine BNigrosine wl water solubleNigrosine WSB

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
inert_ingredient; non_food_use; PesticidesEPACPCat
banned; Europe; Personal careEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
9YWS9G6WTFUNIIFDA UNII substance identifier--openFDA substances
9YWS9G6WTFUNIIFDA UNII substance identifier--openFDA substances
9YWS9G6WTFUNIIFDA UNII substance identifier--openFDA substances
9YWS9G6WTFUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Colorants
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Nigrosine?

Nigrosine has 4 NOAEL studies in the database. The lowest reported value is 9YWS9G6WTF UNII. Source: openFDA substances.

What regulatory lists include Nigrosine?

Nigrosine appears on 2 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, banned; Europe; Personal care. Source: EPA CPDat.

Is Nigrosine used in cosmetics?

Yes, Nigrosine is also indexed as a cosmetic ingredient under the name CI 50420. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Nigrosine come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Nigrosine used outside industrial chemicals?

Nigrosine also appears in cosmetics databases.