What is the NOAEL for Fennel oil?
Fennel oil has 17 NOAEL studies in the database. The lowest reported value is 1.333 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
Fennel oil
Also known as: Fennel seed oil sweet, Oils, fennel, Bitter fennel oil, FEMA No. 2483, Fennel oil, bitter (+15 more)
CAS 8006-84-6
Fennel oil (CAS 8006-84-6) is a chemical substance. Key regulatory status: 11 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
17
SOURCE
chemical inventory jurisdictions
Regulatory lists
11
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
23 fields
Name
Fennel oil
CAS Number
8006-84-6
DTXSID
DTXSID4044327
Synonyms
Fennel seed oil sweetOils, fennelBitter fennel oilFEMA No. 2483Fennel oil, bitterFennel oil, sweetFennel oil, sweet (Foeniculum vulgare MilL. var. dulce D.C.)FinocchioFlorence fennelFoeniculum vulgare, oilFoeniculum vulgare var. dulce oilOils, foeniculum vulgare
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
18 records
Softener and conditionerHumectantFragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
11 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| IFRA Transparency | IFRA | IFRA |
| IFRA Transparency | IFRA | IFRA |
| Europe; Personal care - body oil | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - dental care - toothpaste | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 17 of 17 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1.667 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1.333 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| 59AAO5F6HT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 59AAO5F6HT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 59AAO5F6HT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 59AAO5F6HT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 12 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2520 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 2835 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 7087 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 1125 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 900 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| =50 | mg/kg bw/day | NOEL | injection | Mouse | ToxValDB_ECOTOX |
| 2 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 17 of 17 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
essential oil
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Fennel oil?
Fennel oil appears on 7 regulatory/inventory lists including IFRA Transparency, consumer_product, Europe; Personal care - body oil, and 4 more. Source: EPA CPDat.
Is Fennel oil used in cosmetics?
Yes, Fennel oil is also indexed as a cosmetic ingredient under the name Foeniculum Vulgare Oil. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Fennel oil come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Fennel oil used outside industrial chemicals?
Fennel oil also appears in cosmetics, cannabis databases.