What is the GHS hazard classification for Coal tar?
Coal tar (CAS 8007-45-2) is classified under EU CLP Annex VI as Carc. 1A with signal word Danger. Hazard statements: H350. Source: EU CLP Annex VI (ECHA).
Danger
GHS08
NOAEL Data
IARC Group 1
Cosmetic Ingredient
Coal tar
Also known as: OILS, COAL TAR LIGHT, Carbo-cort, Caswell No. 223, Crude coal tar, EINECS 232-361-7 (+6 more)
CAS 8007-45-2
Coal tar (CAS 8007-45-2) is a chemical substance with GHS signal word Danger; key hazard signal: H350. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, IARC.
Cross-Vertical Regulatory Divergence
Coal tar is prohibited in EU cosmetics at max 0% but has active industrial GHS classifications (H350).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
28
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Danger
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Coal tar
CAS Number
8007-45-2
DTXSID
DTXSID1027683
Synonyms
OILS, COAL TAR LIGHTCarbo-cortCaswell No. 223Crude coal tarEINECS 232-361-7EPA Pesticide Chemical Code 022003ImpervotarPicis carbonisPolytar bathCoal tarsUNII-R533ESO2EC
IARC Carcinogen Classification
Carcinogenic hazard classification from IARC monograph evaluations.
SOURCE
IARC Monographs on the Identification of Carcinogenic Hazards to Humans
1 records
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 1 | Carcinogenic to humans | 2009 | 92, 100F |
GHS / CLP Classification
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
SOURCE
EU CLP Annex VI (ECHA)
1 classifications
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Carc. 1A | H350 | GHS08 | Danger |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
BiocideAnti-dandruffCatalyst
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Cons electronics mech appliances and machinery; Europe | Danish Environmental Protection Agency | Danish EPA |
| Canada; pharmaceutical | DrugBank | DrugBank |
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 28 of 28 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| R533ESO2EC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R533ESO2EC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R533ESO2EC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R533ESO2EC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 1 | unitless | IARC group | - | - | NTP_ICE_cancer |
| =1.1 | mg/day | LOEL | oral | Mouse | ToxValDB_ECOTOX |
| =1.2 | mg/day | LOEL | oral | Mouse | ToxValDB_ECOTOX |
| =2.5 | mg/org-day | LOEL | oral | Mouse | ToxValDB_ECOTOX |
| =5 | mg/day | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =6 | % | LOEL | dermal | Mouse | ToxValDB_ECOTOX |
| =17.1 | ppm | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =25 | mg/day | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =47.9 | ppm | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =100 | ul/org | LOEL | dermal | Rat | ToxValDB_ECOTOX |
| =500 | ul/org | LOEL | dermal | Rat | ToxValDB_ECOTOX |
| =3100 | mg/kg bw/day | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =0.35 | mg/day | NOEL | oral | Mouse | ToxValDB_ECOTOX |
| =5 | mg/day | NOEL | injection | Rat | ToxValDB_ECOTOX |
| =29.2 | ppm | NOEL | oral | Rat | ToxValDB_ECOTOX |
Showing 28 of 28 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
0%
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
404
Bioactivity
0
Frequently Asked Questions
What is the NOAEL for Coal tar?
Coal tar has 28 NOAEL studies in the database. The lowest reported value is R533ESO2EC UNII. Source: openFDA substances.
What regulatory lists include Coal tar?
Coal tar appears on 4 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Cons electronics mech appliances and machinery; Europe, Canada; pharmaceutical, and 1 more. Source: EPA CPDat.
Is Coal tar a carcinogen according to IARC?
Coal tar is classified by IARC as Group 1 — carcinogenic to humans (evaluated 2009). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Is Coal tar used in cosmetics?
Yes, Coal tar is also indexed as a cosmetic ingredient under the name Coal Tar. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Coal tar come from?
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Coal tar have different safety status in cosmetics vs industrial chemicals?
Coal tar is prohibited in EU cosmetics at max 0% but has active industrial GHS classifications (H350).
Is Coal tar used outside industrial chemicals?
Coal tar also appears in cosmetics, pharmaceutical databases.