What is the NOAEL for Oils, verbena?
Oils, verbena has 9 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP ICE skin sensitization.
NOAEL Data
Cosmetic Ingredient
Oils, verbena
Also known as: Lippia citriodora oil, Verbena absolute, Verbena (Lippia citriodora hbk.), Verbena oil
CAS 8024-12-2
Oils, verbena (CAS 8024-12-2) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS.
View cosmetic safety profile for Verbena Officinalis Leaf Absolute →
SOURCE
NOAEL studies
NOAEL studies
9
SOURCE
Chemical inventory jurisdictions
Regulatory lists
4
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
Oils, verbena
CAS Number
8024-12-2
Synonyms
Lippia citriodora oilVerbena absoluteVerbena (Lippia citriodora hbk.)Verbena oil
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
12 records
AntioxidantDeodorizerFlavouring and nutrientFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| banned; Europe; Personal care | European Commission | CosIng |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 7.8 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 6 | % | Concentration, one positive response | Dermal | Human | NTP ICE skin sensitization |
| 0 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 7.692 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 8100 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 5265 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 4050 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP ICE skin sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 9 of 9 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
SCCS Opinions
EU Scientific Committee opinions tied to the matched substance.
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SCCS Opinion
2 opinions
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCP/1046/07 | 21 March 2007 | Insufficient data - SCCP recognises contradiction between prior opinions; further information required before conclusion can be drawn. Crude verbena oil banned; absolute restricted to ≤0.2% | ≤0.2% absolute in finished cosmetic products (prior SCCNFP/0392/00 restriction pending clarification) | Conflicting prior opinions (SCCNFP/0320/00 vs SCCNFP/0392/00); sensitisation potential confirmed; botanical identity clarification needed; modern conforming sensitisation studies required |
| SCCP/1073/06 | 2007-03-21 | The SCCP recognises contradiction in the entries on 'Verbena (Lippia citriodora Kunth)' in the respective opinions. However, and in order to respond to the questions asked, the following information is required: clarification of the botanical identity ...; chemical identification/characterisation of fragrance ingredients derived from 'Verbena (Lippia citriodora Kunth); sensitisation studies ... conforming to current standards and guidelines. | - | Clarification opinion on contradictory prior entries; SCCP cannot resolve without botanical identity clarification, chemical identification/characterisation, and current-standard sensitisation studies. Based on sensitising potential. |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Oils, verbena?
Oils, verbena appears on 3 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, banned; Europe; Personal care. Source: EPA CPDat.
Is Oils, verbena used in cosmetics?
Yes, Oils, verbena is also indexed as a cosmetic ingredient under the name Verbena Officinalis Leaf Absolute. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Oils, verbena come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Oils, verbena used outside industrial chemicals?
Oils, verbena also appears in cosmetics, food safety databases.