What is the NOAEL for HC Orange 3?
HC Orange 3 has 7 NOAEL studies in the database. The lowest reported value is 428754S94Z UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
HC Orange 3
CAS 81612-54-6
HC Orange 3 (CAS 81612-54-6) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
NOAEL studies
NOAEL studies
7
SOURCE
Chemical inventory jurisdictions
Regulatory lists
1
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
5 fields
Name
HC Orange 3
CAS Number
81612-54-6
Molecular Formula
C11H16N2O6
InChI Key
SZWQTBKBBNGUAB-UHFFFAOYSA-N
Monoisotopic Mass
272.100836
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 428754S94Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 100 | mg/kg bw/day | LOAEL | oral | rat | COSMOS DB |
| =100 | mg/kg bw/day | NOAEL | - | rat | SCCNFP Opinion |
| =300 | mg/kg bw/day | NOAEL | - | rat | SCCNFP Opinion |
| 100 | mg/kg bw/day | repeated dose toxicity | - | rat | Regulatory source |
| 300 | mg/kg bw/day | repeated dose toxicity | - | rat | Regulatory source |
| 100 | mg/kg bw/day | sensitisation | oral | rat | Regulatory source |
Showing 7 of 7 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Frequently Asked Questions
What regulatory lists include HC Orange 3?
HC Orange 3 appears on 1 regulatory/inventory list including banned; Europe; Personal care. Source: EPA CPDat.
Is HC Orange 3 used in cosmetics?
Yes, HC Orange 3 is also indexed as a cosmetic ingredient under the name HC Orange No. 3. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for HC Orange 3 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is HC Orange 3 used outside industrial chemicals?
HC Orange 3 also appears in cosmetics databases.