What is the NOAEL for Butyryl-n-trihexylcitrate?
Butyryl-n-trihexylcitrate has 6 NOAEL studies in the database. The lowest reported value is M4974DI70C UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Butyryl-n-trihexylcitrate
Also known as: N-BUTYRYL TRI-N-HEXYL CITRATE, 1,2,3-Propanetricarboxylic acid, 2-(1-oxobutoxy)-, 1,2,3-trihexyl ester, 1,2,3-Propanetricarboxylic acid, 2-(1-oxobutoxy)-, trihexyl ester, Butyryl trihexyl citrate
CAS 82469-79-2
Butyryl-n-trihexylcitrate (CAS 82469-79-2) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Butyroyl Trihexyl Citrate →
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Butyryl-n-trihexylcitrate
CAS Number
82469-79-2
DTXSID
DTXSID0047535
Molecular Formula
C28H50O8
InChI Key
GWVUTNGDMGTPFE-UHFFFAOYSA-N
Monoisotopic Mass
514.350569
Synonyms
N-BUTYRYL TRI-N-HEXYL CITRATE1,2,3-Propanetricarboxylic acid, 2-(1-oxobutoxy)-, 1,2,3-trihexyl ester1,2,3-Propanetricarboxylic acid, 2-(1-oxobutoxy)-, trihexyl esterButyryl trihexyl citrate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
8 records
Softener and conditionerPlasticizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Europe; plastic_additive | European Chemicals Agency | European Chemicals Agency (ECHA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| M4974DI70C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M4974DI70C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M4974DI70C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M4974DI70C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =500 | mg/kg bw/day | NOEL | injection | Rat | ToxValDB_ECHA_IUCLID |
Showing 6 of 6 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185537
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Butyryl-n-trihexylcitrate?
Butyryl-n-trihexylcitrate appears on 1 regulatory/inventory list including Europe; plastic_additive. Source: EPA CPDat.
Is Butyryl-n-trihexylcitrate used in cosmetics?
Yes, Butyryl-n-trihexylcitrate is also indexed as a cosmetic ingredient under the name Butyroyl Trihexyl Citrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Butyryl-n-trihexylcitrate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Butyryl-n-trihexylcitrate used outside industrial chemicals?
Butyryl-n-trihexylcitrate also appears in cosmetics, pharmaceutical databases.