NOAEL Data Cosmetic Ingredient

Flavianic acid sodium salt

Also known as: 2-Naphthalenesulfonic acid, 8-hydroxy-5,7-dinitro-, sodium salt (1:2), 2-Naphthalenesulfonic acid, 5,7-dinitro-8-hydroxy-, disodium salt, C.I. Acid Yellow 1, disodium 5,7-dinitro-8-oxidonaphthalene-2-sulphonate, 1307 Yellow (+15 more)

CAS 846-70-8

Flavianic acid sodium salt (CAS 846-70-8) is a chemical substance. Key regulatory status: 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS.

View cosmetic safety profile for CI 10316 (Ext. D&C Yellow No. 7) →

SOURCE noael studies public
NOAEL studies
58
SOURCE chemical inventory jurisdictions
Regulatory lists
6
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields
Name
Flavianic acid sodium salt
CAS Number
846-70-8
DTXSID
DTXSID1041718
Molecular Formula
C10H6N2O8S.2Na
InChI Key
CTIQLGJVGNGFEW-UHFFFAOYSA-L
Monoisotopic Mass
359.964025
Synonyms
2-Naphthalenesulfonic acid, 8-hydroxy-5,7-dinitro-, sodium salt (1:2)2-Naphthalenesulfonic acid, 5,7-dinitro-8-hydroxy-, disodium saltC.I. Acid Yellow 1disodium 5,7-dinitro-8-oxidonaphthalene-2-sulphonate1307 Yellow1422 YellowA.F. Yellow No. 1Acid Leather Yellow NYSAmacid Yellow SCalcocid Yellow SDolkwal Naphthol Yellow SEdicol Supra Yellow Y

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 6 records
ListKeywordSource
inert_ingredient; non_food_use; PesticidesEPACPCat
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA
Europe; Personal care; restrictedEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 50 of 58 studies
ValueUnitEndpointRouteSpeciesSource
08F8S9O3I5UNIIFDA UNII substance identifier--openFDA substances
08F8S9O3I5UNIIFDA UNII substance identifier--openFDA substances
08F8S9O3I5UNIIFDA UNII substance identifier--openFDA substances
08F8S9O3I5UNIIFDA UNII substance identifier--openFDA substances
conceptidentifierFDA UNII substance identifier--openFDA substances
conceptidentifierFDA UNII substance identifier--openFDA substances
conceptidentifierFDA UNII substance identifier--openFDA substances
conceptidentifierFDA UNII substance identifier--openFDA substances
30mg/kg bw/dayLOAELoralratCOSMOS_DB
=-mg/kg bw/dayNOAEL-guinea pigSCCNFP_vision_codex
=-mg/kg bw/dayNOAEL-guinea pigSCCNFP_vision_codex
=-mg/kg bw/dayNOAEL-guinea pigSCCNFP_vision_codex
=-mg/kg bw/dayNOAEL-guinea pigSCCNFP_vision_codex
=0.0009mg/kg bwNOAELoralratSCCS_vision_codex
=0.0009mg/kg bwNOAELoralratSCCS_vision_codex
=0.0009mg/kg bwNOAELoralratSCCS_vision_codex
=0.0009mg/kg bwNOAELoralratSCCS_vision_codex
=0.0011mg/kg bwNOAELoralratSCCS_vision_codex
=0.0011mg/kg bwNOAELoralratSCCS_vision_codex
=0.0011mg/kg bwNOAELoralratSCCS_vision_codex
=0.0011mg/kg bwNOAELoralratSCCS_vision_codex
=30mg/kg bw/dayNOAEL--SCCS_vision_codex
=30mg/kg bwNOAELoralratSCCS_vision_codex
=30mg/kg bw/dayNOAELdermal-SCCNFP_vision_codex
=30mg/kg bw/dayNOAEL--SCCS_vision_codex
=30mg/kg bwNOAELoralratSCCS_vision_codex
=30mg/kg bw/dayNOAEL--SCCS_vision_codex
=30mg/kg bwNOAELoralratSCCS_vision_codex
=30mg/kg bw/dayNOAELdermal-SCCNFP_vision_codex
=30mg/kg bw/dayNOAELdermal-SCCNFP_vision_codex
=30mg/kg bw/dayNOAEL--SCCS_vision_codex
=30mg/kg bwNOAELoralratSCCS_vision_codex
=30mg/kg bw/dayNOAELdermal-SCCNFP_vision_codex
=50mg/kg bw/dayNOAEL-humanSCCS_vision_codex
=50mg/kg bw/dayNOAEL-pigSCCNFP_vision_codex
=50mg/kg bw/dayNOAEL-humanSCCS_vision_codex
=50mg/kg bw/dayNOAEL-humanSCCS_vision_codex
=50mg/kg bw/dayNOAEL-pigSCCNFP_vision_codex
=50mg/kg bw/dayNOAEL-pigSCCNFP_vision_codex
=50mg/kg bw/dayNOAEL-humanSCCS_vision_codex
=50mg/kg bw/dayNOAEL-pigSCCNFP_vision_codex
=0.0009mg/kg bwdermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=0.0011mg/kg bwdermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=30mg/kg bwdermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=30mg/kg bwdermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=30mg/kg bwdermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=30mg/kg bwdermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
-mg/kg bw/daydevelopmental toxicity-guinea pigUnifiedCodex:SCCNFP:beta.noael_studies
30mg/kg bw/daydevelopmental toxicity-humanUnifiedCodex:SCCS_SHADOW:beta.noael_studies
30mg/kg bw/daydevelopmental toxicity-humanUnifiedCodex:SCCS_SHADOW:beta.noael_studies

Showing 50 of 58 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

SCCS Opinions

EU Scientific Committee opinions tied to the matched substance.

SOURCE EU SCCS 1 opinions
OpinionDateConclusionMax Conc.Concerns
SCCP/1179/0816 December 2008not safe-low MoS; sensitisation; genotoxicity concerns

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
Permitted in all cosmetics except those applied in the vicinity of the eyes and lip products; no maximum concentration specified
Category
Colorants
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Flavianic acid sodium salt?

Flavianic acid sodium salt has 58 NOAEL studies in the database. The lowest reported value is 08F8S9O3I5 UNII. Source: openFDA substances.

What regulatory lists include Flavianic acid sodium salt?

Flavianic acid sodium salt appears on 3 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Europe; Personal care - hair coloring, Europe; Personal care; restricted. Source: EPA CPDat.

Is Flavianic acid sodium salt used in cosmetics?

Yes, Flavianic acid sodium salt is also indexed as a cosmetic ingredient under the name CI 10316 (Ext. D&C Yellow No. 7). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Flavianic acid sodium salt come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Flavianic acid sodium salt used outside industrial chemicals?

Flavianic acid sodium salt also appears in cosmetics databases.