What is the NOAEL for Butylphthalyl butylglycolate?
Butylphthalyl butylglycolate has 9 NOAEL studies in the database. The lowest reported value is I5LOD5H050 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Butylphthalyl butylglycolate
Also known as: BPBG, Phthalic acid, butyl ester, butyl glycolate, 1,2-Benzenedicarboxylic acid, 1-(2-butoxy-2-oxoethyl) 2-butyl ester, AI3-01793, BRN 2007363 (+14 more)
CAS 85-70-1
Butylphthalyl butylglycolate (CAS 85-70-1) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Butyl Phthalyl Butyl Glycolate →
Cross-Vertical Regulatory Divergence
Butylphthalyl butylglycolate is prohibited in EU cosmetics but has active industrial GHS classifications (H413).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Butylphthalyl butylglycolate
CAS Number
85-70-1
DTXSID
DTXSID7023938
Molecular Formula
C18H24O6
InChI Key
GOJCZVPJCKEBQV-UHFFFAOYSA-N
Monoisotopic Mass
336.157288
Synonyms
BPBGPhthalic acid, butyl ester, butyl glycolate1,2-Benzenedicarboxylic acid, 1-(2-butoxy-2-oxoethyl) 2-butyl esterAI3-01793BRN 2007363Butyl carbobutoxymethyl phthalateButyl phthalate butyl glycolateButylcarbobutoxymethyl phthalateCaswell No. 131BDibutyl O-(o-carboxybenzoyl) glycolateDibutyl O-(o-carboxybenzoyl)glycolateDibutyl o-carboxybenzoyloxyacetate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
Film formerPlasticizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| I5LOD5H050 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I5LOD5H050 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I5LOD5H050 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I5LOD5H050 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =7000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1000 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_IRIS |
| =1000 | mg/kg/day | NOEL | oral | - | EPA_IRIS_iris_rfd_systems.csv |
| =1 | mg/kg bw/day | RfD | oral | Human | ToxValDB_IRIS |
| =1 | mg/kg/day | RfD | oral | - | EPA_IRIS_iris_rfd_systems.csv |
Showing 9 of 9 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Solvent
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3182027
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Butylphthalyl butylglycolate?
Butylphthalyl butylglycolate appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Indirect additives food contact (10/2018). Source: EPA CPDat.
Is Butylphthalyl butylglycolate used in cosmetics?
Yes, Butylphthalyl butylglycolate is also indexed as a cosmetic ingredient under the name Butyl Phthalyl Butyl Glycolate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Butylphthalyl butylglycolate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Butylphthalyl butylglycolate have different safety status in cosmetics vs industrial chemicals?
Butylphthalyl butylglycolate is prohibited in EU cosmetics but has active industrial GHS classifications (H413).
Is Butylphthalyl butylglycolate used outside industrial chemicals?
Butylphthalyl butylglycolate also appears in cosmetics, pharmaceutical, cannabis databases.