What is the NOAEL for Sodium hydroxymethanesulfonate?
Sodium hydroxymethanesulfonate has 4 NOAEL studies in the database. The lowest reported value is I566KHA05F UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium hydroxymethanesulfonate
Also known as: EINECS 212-800-9, Formaldehyde, compd with monosodium sulfite (1:1), Formaldehyde, compd with sodium hydrogen sulfate (1:1), Formaldehyde-sodium bisulfite compound, Methylolsulfonic acid sodium salt (+5 more)
CAS 870-72-4
Sodium hydroxymethanesulfonate (CAS 870-72-4) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Sodium Hydroxymethane Sulfonate ⚠️ CRITICAL →
Cross-Vertical Regulatory Divergence
Sodium hydroxymethanesulfonate is prohibited in EU cosmetics at max 0.2% but has active industrial GHS classifications.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Sodium hydroxymethanesulfonate
CAS Number
870-72-4
DTXSID
DTXSID3027328
Molecular Formula
CH4O4S.Na
InChI Key
UOULCEYHQNCFFH-UHFFFAOYSA-M
Synonyms
EINECS 212-800-9Formaldehyde, compd with monosodium sulfite (1:1)Formaldehyde, compd with sodium hydrogen sulfate (1:1)Formaldehyde-sodium bisulfite compoundMethylolsulfonic acid sodium saltNSC 2441Sodium formaldehydebisulfiteSulfuric acid, monosodium salt, compd with formaldehyde (1:1)Sulfurous acid, monosodium salt, compd with formaldehyde (1:1)UNII-I566KHA05F
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
BiocideReducing agent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| I566KHA05F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I566KHA05F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I566KHA05F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =3200 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium hydroxymethanesulphonate | 212-800-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
0.2%
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185494
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is Sodium hydroxymethanesulfonate used in cosmetics?
Yes, Sodium hydroxymethanesulfonate is also indexed as a cosmetic ingredient under the name Sodium Hydroxymethane Sulfonate ⚠️ CRITICAL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium hydroxymethanesulfonate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Sodium hydroxymethanesulfonate have different safety status in cosmetics vs industrial chemicals?
Sodium hydroxymethanesulfonate is prohibited in EU cosmetics at max 0.2% but has active industrial GHS classifications.
Is Sodium hydroxymethanesulfonate used outside industrial chemicals?
Sodium hydroxymethanesulfonate also appears in cosmetics, pharmaceutical databases.