What is the NOAEL for Mandelic acid?
Mandelic acid has 4 NOAEL studies in the database. The lowest reported value is NH496X0UJX UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Mandelic acid
Also known as: Benzeneacetic acid, .alpha.-hydroxy-, Benzeneacetic acid, alpha-hydroxy-, EINECS 202-007-6, EINECS 210-277-1, Glycolic acid, phenyl- (+15 more)
CAS 90-64-2
Mandelic acid (CAS 90-64-2) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Mandelic acid is classified GHS Danger (H302, H315, H318, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Mandelic acid
CAS Number
90-64-2
DTXSID
DTXSID6023234
Molecular Formula
C8H8O3
InChI Key
IWYDHOAUDWTVEP-UHFFFAOYSA-N
Monoisotopic Mass
152.047344
Synonyms
Benzeneacetic acid, .alpha.-hydroxy-Benzeneacetic acid, alpha-hydroxy-EINECS 202-007-6EINECS 210-277-1Glycolic acid, phenyl-p-Mandelic acidRacemic mandelic acidalpha-Toluic acid, alpha-hydroxy-2-Hydroy-2-phenylacetic acidKyselina 2-fenyl-2-hydroxyethanovaKyselina mandlovaUNII-NH496X0UJX
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
BiocideNo specific technical function
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| NH496X0UJX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NH496X0UJX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NH496X0UJX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NH496X0UJX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Mandelic acid | 202-007-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
MANDELIC ACID
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
What regulatory lists include Mandelic acid?
Mandelic acid appears on 2 regulatory/inventory lists including Canada; pharmaceutical, pharmaceutical. Source: EPA CPDat.
Is Mandelic acid used in cosmetics?
Yes, Mandelic acid is also indexed as a cosmetic ingredient under the name Mandelic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Mandelic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Mandelic acid have different safety status in cosmetics vs industrial chemicals?
Mandelic acid is classified GHS Danger (H302, H315, H318, H335) in the chemicals database but is allowed in EU cosmetics.
Is Mandelic acid used outside industrial chemicals?
Mandelic acid also appears in cosmetics, pharmaceutical databases.