What is the NOAEL for Hydrotropic aldehyde dimethyl acetal?
Hydrotropic aldehyde dimethyl acetal has 8 NOAEL studies in the database. The lowest reported value is H41WGL6C12 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Hydrotropic aldehyde dimethyl acetal
Also known as: 2-Phenylpropionaldehyde dimethyl acetal, Benzene, (2,2-dimethoxy-1-methylethyl)-, BRN 2091958, (2,2-Dimethoxy-1-methylethyl)benzene, 1,1-Dimethoxy-2-phenylpropane (+10 more)
CAS 90-87-9
Hydrotropic aldehyde dimethyl acetal (CAS 90-87-9) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Hydrotropic aldehyde dimethyl acetal is prohibited in EU cosmetics but has active industrial GHS classifications (H302).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
Hydrotropic aldehyde dimethyl acetal
CAS Number
90-87-9
DTXSID
DTXSID6047109
Molecular Formula
C11H16O2
InChI Key
UFOUDYPOSJJEDJ-UHFFFAOYSA-N
Monoisotopic Mass
180.11503
Synonyms
2-Phenylpropionaldehyde dimethyl acetalBenzene, (2,2-dimethoxy-1-methylethyl)-BRN 2091958(2,2-Dimethoxy-1-methylethyl)benzene1,1-Dimethoxy-2-phenylpropaneEINECS 202-022-8FEMA No. 2888Hydratropaldehyde dimethyl acetalHydratropic aldehyde dimethyl acetalHydrotropaldehyde dimethyl acetalalpha-Methylphenacetaldehyde dimethyl acetalNSC 46115
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| H41WGL6C12 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H41WGL6C12 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H41WGL6C12 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H41WGL6C12 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =1850 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-phenylpropionaldehyde-dimethyl acetal | 202-022-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3186598
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Hydrotropic aldehyde dimethyl acetal?
Hydrotropic aldehyde dimethyl acetal appears on 3 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Hydrotropic aldehyde dimethyl acetal used in cosmetics?
Yes, Hydrotropic aldehyde dimethyl acetal is also indexed as a cosmetic ingredient under the name Hydratropic Aldehyde Dimethyl Acetal (2-Phenylpropionaldehyde Dimethyl Acetal). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hydrotropic aldehyde dimethyl acetal come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Hydrotropic aldehyde dimethyl acetal have different safety status in cosmetics vs industrial chemicals?
Hydrotropic aldehyde dimethyl acetal is prohibited in EU cosmetics but has active industrial GHS classifications (H302).
Is Hydrotropic aldehyde dimethyl acetal used outside industrial chemicals?
Hydrotropic aldehyde dimethyl acetal also appears in cosmetics, pharmaceutical, food safety, cannabis databases.