What is the NOAEL for Triton X 100?
Triton X 100 has 30 NOAEL studies in the database. The lowest reported value is 7.5 % via Dermal in Mouse. Source: NTP ICE skin sensitization.
NOAEL Data
Cosmetic Ingredient
Triton X 100
Also known as: Poly(oxy-1,2-ethanediyl), alpha-[4-(1,1,3,3-tetramethylbutyl)phenyl]-omega-hydroxy-, polyoxyethylene octyl phenyl ether, Octoxinol 9, OPE 30, OPE 4 (+15 more)
CAS 9002-93-1
Triton X 100 (CAS 9002-93-1) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
NOAEL studies
NOAEL studies
30
SOURCE
Chemical inventory jurisdictions
Regulatory lists
5
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
Triton X 100
CAS Number
9002-93-1
Molecular Formula
C16H26O2
Monoisotopic Mass
250.19328
Synonyms
Poly(oxy-1,2-ethanediyl), alpha-[4-(1,1,3,3-tetramethylbutyl)phenyl]-omega-hydroxy-polyoxyethylene octyl phenyl etherOctoxinol 9OPE 30OPE 4NOP 90Lutensol OP 10Poly(oxy-1,2-ethanediyl), .alpha.-[4-(1,1,3,3-tetramethylbutyl)phenyl]-.omega.-hydroxy-Poly(oxy-1,2-ethanediyl), alpha-(4-(1,1,3,3-tetramethylbutyl)phenyl)-omega-hydroxy-alpha-(p-(1,1,3,3-Tetramethylbutyl)phenyl)-omega-hydroxypoly(oxyethylene) produced by the condensation of 1 mole of p-(1,1,3,3-tetramethylbutyl)phenol with a range of 30-70 moles of ethylene oxideTriton X-100EC No.: 618-344-0
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
51 records
Surfactant (surface active agent)EmulsifierCleaning agentFragranceWetting agent (non-aqueous)Surface modifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| fracking; water | NY Department of Conservation | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| IFRA Transparency | IFRA | IFRA |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 30 of 30 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 15.23 | min | Breakthrough Time | Dermal | - | NTP ICE skin irritation |
| 16.86 | min | Breakthrough Time | Dermal | - | NTP ICE skin irritation |
| 240 | min | Breakthrough Time | Dermal | - | NTP ICE skin irritation |
| 68.7 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP ICE eye irritation |
| 7.5 | % | EC3 | Dermal | Mouse | NTP ICE skin sensitization |
| 17.8 | % | EC3 | Dermal | Mouse | NTP ICE skin sensitization |
| 285 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 297 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 310 | min | ET50 | Dermal | - | NTP ICE skin irritation |
| 3E2NC94VPF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 480KVF3EBY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 48RF3T316O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7JPC6Y25QS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8419DEW37J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GW0EMR6SXY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KI56N6W95G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NR7ZWN391G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QH2U227LZY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SQL994V0M6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| TJ327E1R1V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V772YP1HVB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| X7V411JQHV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | unitless | GHS Classification | Ocular | Rabbit | NTP ICE eye irritation |
| 2 | unitless | GHS Classification | Ocular | Rabbit | NTP ICE eye irritation |
| 0.92 | %/sec | Intensity | Ocular | - | NTP ICE eye irritation |
| =1800 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =1900 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =3800 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| 0 | s | Lag time | Ocular | - | NTP ICE eye irritation |
| 83 | % | Plateau level | Ocular | - | NTP ICE eye irritation |
Showing 30 of 30 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Frequently Asked Questions
What regulatory lists include Triton X 100?
Triton X 100 appears on 5 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), fracking; water, pharmaceutical, and 2 more. Source: EPA CPDat.
Is Triton X 100 used in cosmetics?
Yes, Triton X 100 is also indexed as a cosmetic ingredient under the name Octoxynol-30. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Triton X 100 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Triton X 100 used outside industrial chemicals?
Triton X 100 also appears in cosmetics databases.