What is the NOAEL for Dextran?
Dextran has 65 NOAEL studies in the database. The lowest reported value is 200 ug/mL via Dermal. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
Dextran
Also known as: Dextran 40,70,110, Dextranum 40,70, EINECS 232-677-5, Low molecular dextran-L, Polyglucinum (+15 more)
CAS 9004-54-0
Dextran (CAS 9004-54-0) is a chemical substance. Key regulatory status: 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract) →
SOURCE
noael studies public
NOAEL studies
65
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
23 fields
Name
Dextran
CAS Number
9004-54-0
DTXSID
DTXSID8020385
Synonyms
Dextran 40,70,110Dextranum 40,70EINECS 232-677-5Low molecular dextran-LPolyglucinumDextranumUNII-7SA290YK68UNII-K3R6ZDH4DUUNII-ZNJ8R24I7ZUNII-65DL069QBPUNII-21C3YS80Q6UNII-42N66Q2197
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
11 records
Viscosity modifierBinderFillerProcessing aids not otherwise specifiedThickening agentSurface modifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 50 of 65 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| >200 | ug/mL | CD86, EC150 | Dermal | - | NTP_ICE_skin_sensitization |
| 5000 | ug/mL | CV75 | Dermal | - | NTP_ICE_skin_sensitization |
| >2000 | uM | EC1.5 | Dermal | - | NTP_ICE_skin_sensitization |
| 05Q25F6XJ3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 05Q25F6XJ3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 05Q25F6XJ3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 05Q25F6XJ3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 21C3YS80Q6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 21C3YS80Q6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 21C3YS80Q6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 21C3YS80Q6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 41Z0077J45 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 41Z0077J45 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 41Z0077J45 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 41Z0077J45 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 42N66Q2197 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 42N66Q2197 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 42N66Q2197 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 42N66Q2197 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 65DL069QBP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 65DL069QBP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 65DL069QBP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 65DL069QBP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7C8S056150 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7C8S056150 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7C8S056150 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7C8S056150 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7SA290YK68 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7SA290YK68 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7SA290YK68 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7SA290YK68 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B854H05S7D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B854H05S7D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B854H05S7D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B854H05S7D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E8A73H7RG1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E8A73H7RG1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E8A73H7RG1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E8A73H7RG1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| EW7Q6SVD0D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| EW7Q6SVD0D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| EW7Q6SVD0D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| EW7Q6SVD0D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K3R6ZDH4DU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K3R6ZDH4DU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K3R6ZDH4DU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K3R6ZDH4DU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P8272ET3N5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P8272ET3N5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P8272ET3N5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 50 of 65 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Dextran?
Dextran appears on 4 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), pharmaceutical, Canada; pharmaceutical, and 1 more. Source: EPA CPDat.
Is Dextran used in cosmetics?
Yes, Dextran is also indexed as a cosmetic ingredient under the name Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dextran come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Dextran used outside industrial chemicals?
Dextran also appears in cosmetics, food safety databases.