NOAEL Data Cosmetic Ingredient

Hydroxypropyl cellulose

Also known as: Hydroxypropylcellulose of low substitution, Hyprolosum, UNII-RFW2ET671P, UNII-2165RE0K14, UNII-5Y0974F5PW (+5 more)

CAS 9004-64-2

Hydroxypropyl cellulose (CAS 9004-64-2) is a chemical substance. Key regulatory status: 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Hydroxypropyl Cellulose →

SOURCE noael studies public
NOAEL studies
74
SOURCE chemical inventory jurisdictions
Regulatory lists
6
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 13 fields
Name
Hydroxypropyl cellulose
CAS Number
9004-64-2
DTXSID
DTXSID6044270
Synonyms
Hydroxypropylcellulose of low substitutionHyprolosumUNII-RFW2ET671PUNII-2165RE0K14UNII-5Y0974F5PWUNII-66O7AQV0RTUNII-8VAB711C5EUNII-U3JF91U133UNII-UKE75GEA7FUNII-VQ8ZWO78F6

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 48 records
FillerFilm formerEmulsifierViscosity modifierBinderStabilizing agentThickening agentProcessing aids not otherwise specified

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 6 records
ListKeywordSource
inert_ingredient; PesticidesEPACPCat
inert_ingredient; non_food_use; PesticidesEPACPCat
drinking_water; Europe; manufacturing; plastic_additiveBelgaquaCPCat
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
SCIL (9/2019)USEPASafer Chemical Ingredients List
Canada; pharmaceuticalDrugBankDrugBank

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 50 of 74 studies
ValueUnitEndpointRouteSpeciesSource
0A7M0N7SPEUNIIFDA UNII substance identifier--openFDA substances
0A7M0N7SPEUNIIFDA UNII substance identifier--openFDA substances
0A7M0N7SPEUNIIFDA UNII substance identifier--openFDA substances
0A7M0N7SPEUNIIFDA UNII substance identifier--openFDA substances
1L0RPI3ASPUNIIFDA UNII substance identifier--openFDA substances
1L0RPI3ASPUNIIFDA UNII substance identifier--openFDA substances
1L0RPI3ASPUNIIFDA UNII substance identifier--openFDA substances
1L0RPI3ASPUNIIFDA UNII substance identifier--openFDA substances
2165RE0K14UNIIFDA UNII substance identifier--openFDA substances
2165RE0K14UNIIFDA UNII substance identifier--openFDA substances
2165RE0K14UNIIFDA UNII substance identifier--openFDA substances
2165RE0K14UNIIFDA UNII substance identifier--openFDA substances
599BTP6K9FUNIIFDA UNII substance identifier--openFDA substances
599BTP6K9FUNIIFDA UNII substance identifier--openFDA substances
599BTP6K9FUNIIFDA UNII substance identifier--openFDA substances
599BTP6K9FUNIIFDA UNII substance identifier--openFDA substances
5Y0974F5PWUNIIFDA UNII substance identifier--openFDA substances
5Y0974F5PWUNIIFDA UNII substance identifier--openFDA substances
5Y0974F5PWUNIIFDA UNII substance identifier--openFDA substances
5Y0974F5PWUNIIFDA UNII substance identifier--openFDA substances
66O7AQV0RTUNIIFDA UNII substance identifier--openFDA substances
66O7AQV0RTUNIIFDA UNII substance identifier--openFDA substances
66O7AQV0RTUNIIFDA UNII substance identifier--openFDA substances
66O7AQV0RTUNIIFDA UNII substance identifier--openFDA substances
7773C1ROEUUNIIFDA UNII substance identifier--openFDA substances
7773C1ROEUUNIIFDA UNII substance identifier--openFDA substances
7773C1ROEUUNIIFDA UNII substance identifier--openFDA substances
7773C1ROEUUNIIFDA UNII substance identifier--openFDA substances
8VAB711C5EUNIIFDA UNII substance identifier--openFDA substances
8VAB711C5EUNIIFDA UNII substance identifier--openFDA substances
8VAB711C5EUNIIFDA UNII substance identifier--openFDA substances
8VAB711C5EUNIIFDA UNII substance identifier--openFDA substances
9XZ8H6N6OHUNIIFDA UNII substance identifier--openFDA substances
9XZ8H6N6OHUNIIFDA UNII substance identifier--openFDA substances
9XZ8H6N6OHUNIIFDA UNII substance identifier--openFDA substances
9XZ8H6N6OHUNIIFDA UNII substance identifier--openFDA substances
BMJ7J4127KUNIIFDA UNII substance identifier--openFDA substances
BMJ7J4127KUNIIFDA UNII substance identifier--openFDA substances
BMJ7J4127KUNIIFDA UNII substance identifier--openFDA substances
BMJ7J4127KUNIIFDA UNII substance identifier--openFDA substances
KZQ570MOA5UNIIFDA UNII substance identifier--openFDA substances
KZQ570MOA5UNIIFDA UNII substance identifier--openFDA substances
KZQ570MOA5UNIIFDA UNII substance identifier--openFDA substances
KZQ570MOA5UNIIFDA UNII substance identifier--openFDA substances
NZ94SDL6WRUNIIFDA UNII substance identifier--openFDA substances
NZ94SDL6WRUNIIFDA UNII substance identifier--openFDA substances
NZ94SDL6WRUNIIFDA UNII substance identifier--openFDA substances
NZ94SDL6WRUNIIFDA UNII substance identifier--openFDA substances
R67D5N7LRSUNIIFDA UNII substance identifier--openFDA substances
R67D5N7LRSUNIIFDA UNII substance identifier--openFDA substances

Showing 50 of 74 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Thickeners
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

E463 — ADI: NOT SPECIFIED mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Hydroxypropyl cellulose?

Hydroxypropyl cellulose has 74 NOAEL studies in the database. The lowest reported value is 0A7M0N7SPE UNII. Source: openFDA substances.

What regulatory lists include Hydroxypropyl cellulose?

Hydroxypropyl cellulose appears on 6 regulatory/inventory lists including inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, drinking_water; Europe; manufacturing; plastic_additive, and 3 more. Source: EPA CPDat.

Is Hydroxypropyl cellulose used in cosmetics?

Yes, Hydroxypropyl cellulose is also indexed as a cosmetic ingredient under the name Hydroxypropyl Cellulose. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Hydroxypropyl cellulose come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Hydroxypropyl cellulose used outside industrial chemicals?

Hydroxypropyl cellulose also appears in cosmetics, food safety, cannabis databases.