Danger GHS06GHS05 NOAEL Data REACH Registered Cosmetic Ingredient

N,N-Diethyl-p-phenylenediamine

Also known as: p-Amino-N,N-diethylaniline, p-(Diethylamino)aniline, 4-(Diethylamino)aniline, N,N-Diethyl-1,4-benzenediamine, N,N-Diethylbenzene-1,4-diamine (+14 more)

CAS 93-05-0

N,N-Diethyl-p-phenylenediamine (CAS 93-05-0) is a chemical substance with GHS signal word Danger; key hazard signal: H301; H314. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for N,N-DIETHYL-P-PHENYLENEDIAMINE →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 25 fields
Name
N,N-Diethyl-p-phenylenediamine
CAS Number
93-05-0
DTXSID
DTXSID2025058
Molecular Formula
C10H16N2
InChI Key
QNGVNLMMEQUVQK-UHFFFAOYSA-N
Monoisotopic Mass
164.131349
Synonyms
p-Amino-N,N-diethylanilinep-(Diethylamino)aniline4-(Diethylamino)anilineN,N-Diethyl-1,4-benzenediamineN,N-Diethylbenzene-1,4-diamine1,4-Benzenediamine, N1,N1-diethyl-p-Phenylenediamine, N,N-diethyl-1,4-Benzenediamine, N,N-diethyl-N1,N1-Diethyl-1,4-benzenediamineN,N-Diethyl-1,4-phenylenediaminePPD 894-Amino-N,N-diethylaniline

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Acute Tox. 3 *; Skin Corr. 1BH301; H314GHS06; GHS05Danger

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Dye

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
0QQA4DFV2JUNIIFDA UNII substance identifier--openFDA substances
0QQA4DFV2JUNIIFDA UNII substance identifier--openFDA substances
0QQA4DFV2JUNIIFDA UNII substance identifier--openFDA substances
0QQA4DFV2JUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered4-amino-N,N-diethylaniline202-214-1ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
II/1311
Category
Hair Dyes
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL1452158
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
View full pharmaceutical profile →

Frequently Asked Questions

What is the GHS hazard classification for N,N-Diethyl-p-phenylenediamine?

N,N-Diethyl-p-phenylenediamine (CAS 93-05-0) is classified under EU CLP Annex VI as Acute Tox. 3 *; Skin Corr. 1B with signal word Danger. Hazard statements: H301; H314. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for N,N-Diethyl-p-phenylenediamine?

N,N-Diethyl-p-phenylenediamine has 4 NOAEL studies in the database. The lowest reported value is 0QQA4DFV2J UNII. Source: openFDA substances.

Is N,N-Diethyl-p-phenylenediamine used in cosmetics?

Yes, N,N-Diethyl-p-phenylenediamine is also indexed as a cosmetic ingredient under the name N,N-DIETHYL-P-PHENYLENEDIAMINE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for N,N-Diethyl-p-phenylenediamine come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Does N,N-Diethyl-p-phenylenediamine have different safety status in cosmetics vs industrial chemicals?

N,N-Diethyl-p-phenylenediamine is classified GHS Danger (H301, H314) in the chemicals database but is restricted in EU cosmetics at max II/1311.

Is N,N-Diethyl-p-phenylenediamine used outside industrial chemicals?

N,N-Diethyl-p-phenylenediamine also appears in cosmetics, pharmaceutical databases.