What is the NOAEL for N,N'-Dimethylurea?
N,N'-Dimethylurea has 10 NOAEL studies in the database. The lowest reported value is WAM6DR9I4X UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
N,N'-Dimethylurea
Also known as: N,N-Dimethylurea, BRN 1740672, EINECS 202-498-7, N,N'-Dimethylharnstoff, UNII-WAM6DR9I4X
CAS 96-31-1
N,N'-Dimethylurea (CAS 96-31-1) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
N,N'-Dimethylurea
CAS Number
96-31-1
DTXSID
DTXSID5025156
Molecular Formula
C3H8N2O
InChI Key
MGJKQDOBUOMPEZ-UHFFFAOYSA-N
Monoisotopic Mass
88.063663
Synonyms
N,N-DimethylureaBRN 1740672EINECS 202-498-7N,N'-DimethylharnstoffUNII-WAM6DR9I4X
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | WARNING |
| GHS Hazard Statements | Causes mild skin irritation Causes eye irritation |
| Short-term Effects | The substance is mildly irritating to the eyes and skin. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| WAM6DR9I4X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WAM6DR9I4X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WAM6DR9I4X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WAM6DR9I4X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =150 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =500 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =30 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =60 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1,3-dimethylurea | 202-498-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1234380
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is N,N'-Dimethylurea used in cosmetics?
Yes, N,N'-Dimethylurea is also indexed as a cosmetic ingredient under the name Dimethyl Urea. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N,N'-Dimethylurea come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is N,N'-Dimethylurea used outside industrial chemicals?
N,N'-Dimethylurea also appears in cosmetics, pharmaceutical databases.