Also known as: 4-09-00-00721, Benzaldehyde, alpha-chloro-, Benzoic acid, chloride, BRN 0471389, alpha-Chlorobenzaldehyde (+2 more)
CAS 98-88-4
Benzoyl chloride (CAS 98-88-4) is a chemical substance with GHS signal word Danger; key hazard signal: H332; H312; H302; H314; H317. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC, OSHA, EPA TRI.
Benzoyl chloride is prohibited in EU cosmetics but has active industrial GHS classifications (H332, H312, H302, H314, H317).
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B; Skin Sens. 1 | H332; H312; H302; H314; H317 | GHS07; GHS05 | Danger |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| Short-term Effects | Lachrymation. The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour or aerosol may cause lung oedema. See Notes. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation and by ingestion. |
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| ACGIH | CEILING | 0.5 ppm [1992] | 0.5 | - | N |
| CAL/OSHA | CEILING | 0.2 ppm (1.1 mg/m³) | 0.2 | 1.1 | N |
| NIOSH | IDLH | 10 mg/m³ | - | 10 | - |
| AIHA | ERPG-1 | 0.3 ppm | 0.3 | - | - |
| AIHA | ERPG-2 | 5 ppm | 5 | - | - |
| AIHA | ERPG-3 | 20 ppm | 20 | - | - |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| VTY8706W36 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VTY8706W36 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VTY8706W36 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VTY8706W36 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1.87 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =1900 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =2460 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =2528 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =2618 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =3619 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =63242.4 | mg/m3 | LEL | inhalation | Human | ToxValDB_DOE_Protective_Action_Criteria |
Showing 11 of 11 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Benzoyl chloride | 202-710-8 | ECHA overview → |
TRI hazard and reporting flags for the matched chemical.
| Chemical | Category | Flags |
|---|---|---|
| Benzoyl chloride | - | - |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Benzoyl chloride (CAS 98-88-4) is classified under EU CLP Annex VI as Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B; Skin Sens. 1 with signal word Danger. Hazard statements: H332; H312; H302; H314; H317. Source: EU CLP Annex VI (ECHA).
Benzoyl chloride has 11 NOAEL studies in the database. The lowest reported value is VTY8706W36 UNII. Source: openFDA substances.
Benzoyl chloride appears on 1 regulatory/inventory list including Indirect additives food contact (10/2018). Source: EPA CPDat.
Occupational exposure limits for Benzoyl chloride are set by ACGIH, CAL/OSHA, NIOSH. 6 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Yes, Benzoyl chloride is also indexed as a cosmetic ingredient under the name Benzoyl Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, EPA Toxics Release Inventory, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Benzoyl chloride is prohibited in EU cosmetics but has active industrial GHS classifications (H332, H312, H302, H314, H317).
Benzoyl chloride also appears in cosmetics, pharmaceutical databases.