Food Safety Substance

Neohesperidin dihydrochalconeE959

Q: What is Neohesperidin dihydrochalcone used for in food?

Neohesperidin dihydrochalcone appears in food-use rows as: Sweetener.

Q: Is Neohesperidin dihydrochalcone / E959 safe?

This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: EFSA ADI <= 5 mg/kg bw/day. EU status evidence: PUBLISHED. US/FDA evidence: FDA has no questions.

Q: What is the ADI for Neohesperidin dihydrochalcone?

Neohesperidin dihydrochalcone has this ADI/reference value in the food-safety tables: EFSA ADI <= 5 mg/kg bw/day. Source: EFSA.

Q: Is Neohesperidin dihydrochalcone also used in cosmetics?

Neohesperidin dihydrochalcone has a same-CAS cosmetics cross-reference: NEOHESPERIDIN DIHYDROCHALCONE, EU status permitted.

Neohesperidin dihydrochalcone (E959) is a food additive with PUBLISHED in the EU, FDA has no questions in the US, and data from 6 regulatory sources.

CAS 20702-77-6 E959 Indexable evidence set

FDA

FDA has no questions

ADI / TDI

EFSA ADI <= 5 mg/kg bw/day

Codex

0 row(s)

SOURCE D1 identity resolution e number aliases | Food Additives | dsstox identifiers | 6 matched regulatory source group(s)

Substance Identity

Resolved identifiers used to render this food-safety record.

Substance name

Neohesperidin dihydrochalcone

CAS

20702-77-6

E-number

E959

DTXSID

DTXSID3025706

PubChem CID

30231

Evidence tier

Indexable evidence set (11)

SOURCE EU Commission FDA | Health Canada | Regulatory source

Multi-Jurisdiction Comparison

Side-by-side status rows for the same resolved substance across public food regulators.

Jurisdiction	Authority	Status	Evidence
European Union	EU Commission	PUBLISHED	EU additive listing; Annex II entry
United States	FDA	FDA has no questions	GRAS notice

SOURCE EU Commission EU Food Additives | EU Food Additives Database Reg 1333 2008

EU Food Additive Status

EU Commission food-additive listing rows from eu_food_additives.

Jurisdiction	E-number	Status	Type	Name	Note
European Union	E959	PUBLISHED	substanceFAD	Neohesperidine DC	-

SOURCE EU Commission EU Annex II Authorised | EU Food Additives Database Reg 1333 2008

EU Annex II Authorised Uses

Authorised additive rows and use conditions from EU Annex II tables.

Jurisdiction	E-number	Name	INS	Policy item	Note
European Union	E959	Neohesperidine DC	-	POL-FAD-IMPORT-3299	-

Conditions and restrictions

Jurisdiction	Food category	Restriction	Comment	Source
European Union	4.2.3 canned or bottled fruit and vegetables	ML 50 mg/kg	only fruit energy-reduced or with no added sugar	Regulatory source
European Union	4.2.4.1 fruit and vegetable preparations excluding compote	ML 50 mg/kg	only energy-reduced	Regulatory source
European Union	4.2.5 jam jellies and marmalades and similar products	ML 50 mg/kg	only energy-reduced jams, jellies and marmalades	Regulatory source
European Union	4.2.5 jam jellies and marmalades and similar products	ML 5 mg/kg	only fruit jellies as flavour enhancer	Regulatory source
European Union	4.2.5.1 Extra jam and extra jelly as defined by Directive 2001/113/EC	ML 50 mg/kg	only energy-reduced jams, jellies and marmalades	Regulatory source
European Union	4.2.5.2 Jam, jellies and marmalades and sweetened chestnut puree as defined by Directive 2001/113/EC	ML 50 mg/kg	only energy-reduced jams, jellies and marmalades	Regulatory source
European Union	4.2.5.2 Jam, jellies and marmalades and sweetened chestnut puree as defined by Directive 2001/113/EC	ML 5 mg/kg	only fruit jellies as flavour enhancer	Regulatory source
European Union	4.2.5.3 other similar fruit or vegetable spreads	ML 50 mg/kg	only energy-reduced fruit or vegetable spreads and dried-fruit-based sandwich spreads, energy-reduced or with no added sugar	Regulatory source
European Union	5.1 Cocoa and chocolate products as covered by Directive 2000/36/EC	ML 100 mg/kg	only energy-reduced or with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 100 mg/kg	only cocoa or dried fruit based, energy-reduced or with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 50 mg/kg	only cocoa, milk, dried-fruit- or fat-based sandwich spreads, energy-reduced or with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 150 mg/kg	only starch based confectionery energy-reduced or with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 100 mg/kg	only confectionery with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 400 mg/kg	only breath-freshening micro-sweets, with no added sugar	Regulatory source
European Union	5.3 chewing gum	ML 150 mg/kg	only with added sugar or polyols, as flavour enhancer	Regulatory source
European Union	5.3 chewing gum	ML 400 mg/kg	only with no added sugar	Regulatory source
European Union	5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4	ML 150 mg/kg	only starch-based confectionery, energy-reduced or with no added sugar	Regulatory source
European Union	5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4	ML 50 mg/kg	only sauces	Regulatory source
European Union	5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4	ML 100 mg/kg	only confectionery with no added sugar	Regulatory source
European Union	5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4	ML 100 mg/kg	only cocoa- or dried fruit-based, energy-reduced or with no added sugar	Regulatory source
European Union	6.3 breakfast cereals	ML 50 mg/kg	only breakfast cereals with a fibre content of more than 15 %, and containing at least 20 % bran, energy reduced or with no added sugar	Regulatory source
European Union	7.2 Fine bakery wares	ML 50 mg/kg	only cornets and wafers, for ice-cream, with no added sugar	Regulatory source
European Union	8.3.1 Non-heat-treated processed meat	ML 5 mg/kg	as flavour enhancer only	Regulatory source
European Union	8.3.2 Heat-treated processed meat	ML 5 mg/kg	as flavour enhancer only, except for foie gras, foie gras entier, blocs de foie gras, Libamáj, libamáj egészben, libamáj tömbben	Regulatory source
European Union	9.2 Processed fish and fishery products including molluscs and crustaceans	ML 30 mg/kg	only sweet-sour preserves and semi-preserves of fish and marinades of fish, crustaceans and molluscs	Regulatory source
European Union	11.4.1 table-top sweeteners in liquid form	quantum satis	-	Regulatory source
European Union	11.4.2 table-top sweeteners in powder form	quantum satis	-	Regulatory source
European Union	11.4.3 table-top sweeteners in tablets	quantum satis	-	Regulatory source
European Union	12.4 Mustard	ML 50 mg/kg	-	Regulatory source
European Union	12.5 Soups and broths	ML 50 mg/kg	only energy-reduced soups	Regulatory source
European Union	12.6 Sauces	ML 50 mg/kg	-	Regulatory source
European Union	12.7 Salads and savoury-based sandwich spreads	ML 50 mg/kg	only Feinkostsalat	Regulatory source
European Union	12.9 Protein products excluding products covered in category 1 8	ML 5 mg/kg	only vegetable protein products, only as flavour enhancer	Regulatory source
European Union	14.1.3 Fruit nectars as defined by Directive 2001/112/EC and vegetable nectars and similar products	ML 30 mg/l	only energy-reduced or with no added sugar	Regulatory source
European Union	14.1.4 Flavoured_drinks	ML 30 mg/l	only energy-reduced or with no added sugar, except milk and milk derivative based flavoured drinks	Regulatory source
European Union	14.1.4 Flavoured_drinks	ML 50 mg/l	only milk and milk derivative based flavoured drinks, energy-reduced or with no added sugar	Regulatory source
European Union	14.2.1 beer and malt beverages	ML 10 mg/l	only alcohol-free beer or with an alcohol content not exceeding 1,2 % vol; 'Bière de table/Tafelbier/Table beer' (original wort content less than 6 %) except for...	Regulatory source
European Union	14.2.1 beer and malt beverages	ML 10 mg/l	only energy-reduced beer	Regulatory source
European Union	14.2.3 Cider and perry	ML 20 mg/l	excluding cydr jakościowy, perry jakościowe, cydr lodowy, perry lodowe	Regulatory source
European Union	14.2.8 Other alcoholic beverages including mixtures of alcoholic beverages with non-alcoholic beverages and other alcoholic beverages based on distilled alcohol with alcoholic strength by volume less than 15 %	ML 30 mg/l	-	Regulatory source
European Union	1.4 flavoured fermented milk products including heat-treated products	ML 50 mg/l	only energy-reduced products or with no added sugar	Regulatory source
European Union	2.2.2 Other fat and oil emulsions including spreads as defined by Regulation (EC) No 1234/2007 and liquid emulsions	ML 5 mg/kg	only as flavour enhancer, only in the fat groups B & C in Annex XV to Regulation (EC) No 1234/2007	Regulatory source
European Union	3 edible ices	ML 50 mg/kg	only energy-reduced or with no added sugar	Regulatory source
European Union	16 Desserts excluding products covered in category 1 3 and 4	ML 50 mg/kg	only energy-reduced or with no added sugar	Regulatory source
European Union	4.2.2 fruit and vegetables in vinegar oil or brine	ML 100 mg/kg	only sweet-sour preserves of fruit and vegetables	Regulatory source
European Union	4.2.3 canned or bottled fruit and vegetables	ML 50 mg/kg	only fruit energy-reduced or with no added sugar	Regulatory source
European Union	4.2.4.1 fruit and vegetable preparations excluding compote	ML 50 mg/kg	only energy-reduced	Regulatory source
European Union	4.2.5 jam jellies and marmalades and similar products	ML 50 mg/kg	only energy-reduced jams, jellies and marmalades	Regulatory source
European Union	4.2.5 jam jellies and marmalades and similar products	ML 5 mg/kg	only fruit jellies as flavour enhancer	Regulatory source
European Union	5.1 Cocoa and chocolate products as covered by Directive 2000/36/EC	ML 100 mg/kg	only energy-reduced or with no added sugar	Regulatory source
European Union	5.3 chewing gum	ML 150 mg/kg	only with added sugar or polyols, as flavour enhancer	Regulatory source
European Union	5.3 chewing gum	ML 400 mg/kg	only with no added sugar	Regulatory source
European Union	6.3 breakfast cereals	ML 50 mg/kg	only breakfast cereals with a fibre content of more than 15 %, and containing at least 20 % bran, energy reduced or with no added sugar	Regulatory source
European Union	8.3.1 Non-heat-treated processed meat	ML 5 mg/kg	as flavour enhancer only	Regulatory source
European Union	8.3.2 Heat-treated processed meat	ML 5 mg/kg	as flavour enhancer only, except for foie gras, foie gras entier, blocs de foie gras, Libamáj, libamáj egészben, libamáj tömbben	Regulatory source
European Union	9.2 Processed fish and fishery products including molluscs and crustaceans	ML 30 mg/kg	only sweet-sour preserves and semi-preserves of fish and marinades of fish, crustaceans and molluscs	Regulatory source
European Union	11.4.1 table-top sweeteners in liquid form	quantum satis	-	Regulatory source
European Union	11.4.2 table-top sweeteners in powder form	quantum satis	-	Regulatory source
European Union	11.4.3 table-top sweeteners in tablets	quantum satis	-	Regulatory source
European Union	12.4 Mustard	ML 50 mg/kg	-	Regulatory source
European Union	12.6 Sauces	ML 50 mg/kg	-	Regulatory source
European Union	15.1 Potato- cereal- flour- or starch-based snacks	ML 50 mg/kg	-	Regulatory source
European Union	15.2 Processed nuts	ML 50 mg/kg	-	Regulatory source
European Union	12.5 Soups and broths	ML 50 mg/kg	only energy-reduced soups	Regulatory source
European Union	12.7 Salads and savoury-based sandwich spreads	ML 50 mg/kg	only Feinkostsalat	Regulatory source
European Union	12.9 Protein products excluding products covered in category 1 8	ML 5 mg/kg	only vegetable protein products, only as flavour enhancer	Regulatory source
European Union	14.2.3 Cider and perry	ML 20 mg/l	excluding cydr jakościowy, perry jakościowe, cydr lodowy, perry lodowe	Regulatory source
European Union	14.2.8 Other alcoholic beverages including mixtures of alcoholic beverages with non-alcoholic beverages and other alcoholic beverages based on distilled alcohol with alcoholic strength by volume less than 15 %	ML 30 mg/l	-	Regulatory source
European Union	4.2.5.1 Extra jam and extra jelly as defined by Directive 2001/113/EC	ML 50 mg/kg	only energy-reduced jams, jellies and marmalades	Regulatory source
European Union	4.2.5.3 other similar fruit or vegetable spreads	ML 50 mg/kg	only energy-reduced fruit or vegetable spreads and dried-fruit-based sandwich spreads, energy-reduced or with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 100 mg/kg	only cocoa or dried fruit based, energy-reduced or with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 50 mg/kg	only cocoa, milk, dried-fruit- or fat-based sandwich spreads, energy-reduced or with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 150 mg/kg	only starch based confectionery energy-reduced or with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 100 mg/kg	only confectionery with no added sugar	Regulatory source
European Union	5.2 Other confectionery including breath freshening micro-sweets	ML 400 mg/kg	only breath-freshening micro-sweets, with no added sugar	Regulatory source
European Union	5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4	ML 150 mg/kg	only starch-based confectionery, energy-reduced or with no added sugar	Regulatory source
European Union	5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4	ML 50 mg/kg	only sauces	Regulatory source
European Union	5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4	ML 100 mg/kg	only confectionery with no added sugar	Regulatory source
European Union	5.4 Decorations, coatings and fillings, except fruit-based fillings covered by category 4.2.4	ML 100 mg/kg	only cocoa- or dried fruit-based, energy-reduced or with no added sugar	Regulatory source
European Union	14.2.1 beer and malt beverages	ML 10 mg/l	only alcohol-free beer or with an alcohol content not exceeding 1,2 % vol; 'Bière de table/Tafelbier/Table beer' (original wort content less than 6 %) except for...	Regulatory source

SOURCE FDA

FDA GRAS Status

US FDA GRAS notice evidence from enriched and notice tables.

Jurisdiction	GRN	Substance	FDA response	Intended use	Basis	Notifier
United States	902	Neohesperidin dihydrochalcone	FDA has no questions	Intended for use as as a sweetener in sweet crackers; biscuits; cornbread, corn muffins, tortillas; other muffins, popovers; other quick breads; fruit juices (with and without...	Scientific procedures	HealthTech BioActives, S.L.U.
United States	902	Neohesperidin dihydrochalcone	FDA has no questions (in PDF)	Intended for use as as a sweetener in sweet crackers; biscuits; cornbread, corn muffins, tortillas; other muffins, popovers; other quick breads; fruit juices (with and without...	Scientific procedures	HealthTech BioActives, S.L.U.

SOURCE Ingredient record GHS classifications

Cross-Reference to Cosmetics / Chemicals / Pharma

Same-CAS public rows from adjacent Roots verticals where available.

SOURCE Cross-vertical comparison Ingredient record | GHS classifications

Cross-Vertical Regulatory Divergence

This substance has different regulatory treatment across food, cosmetics, and industrial use.

CosmeticsNEOHESPERIDIN DIHYDROCHALCONEEU status: permitted Industrial / GHSGHS row foundEuropean Chemicals Agency (ECHA)

SOURCE FAQPage JSON-LD public food renderer rows

Frequently Asked Questions

Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.

What is Neohesperidin dihydrochalcone used for in food?

Neohesperidin dihydrochalcone appears in food-use rows as: Sweetener.

Is Neohesperidin dihydrochalcone / E959 safe?

This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: EFSA ADI <= 5 mg/kg bw/day. EU status evidence: PUBLISHED. US/FDA evidence: FDA has no questions.

What is the ADI for Neohesperidin dihydrochalcone?

Neohesperidin dihydrochalcone has this ADI/reference value in the food-safety tables: EFSA ADI <= 5 mg/kg bw/day. Source: EFSA.

Is Neohesperidin dihydrochalcone also used in cosmetics?

Neohesperidin dihydrochalcone has a same-CAS cosmetics cross-reference: NEOHESPERIDIN DIHYDROCHALCONE, EU status permitted.