Food Safety Substance
alpha-AmylaseE1100
alpha-Amylase (E1100) is a food additive with Not listed as EU additive (processing aid) in the EU, FDA has no questions in the US, and data from 6 regulatory sources.
CAS 9000-90-2
E1100
Indexable evidence set
FDA
FDA has no questions
ADI / TDI
JECFA ADI NOT SPECIFIED
Codex
5 row(s)
SOURCE
D1 identity resolution
e number aliases | Food Additives | dsstox identifiers | 6 matched regulatory source group(s)
Substance Identity
Resolved identifiers used to render this food-safety record.
Substance name
alpha-Amylase
CAS
9000-90-2
E-number
E1100
DTXSID
DTXSID4050435
Evidence tier
Indexable evidence set (10)
SOURCE
EU Commission
FDA | Health Canada | Codex Alimentarius
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| European Union | EU Commission | Not listed as EU additive (processing aid) | - |
| United States | FDA | FDA has no questions | GRAS notice |
| Codex | Codex Alimentarius | Listed | Flour treatment agent |
SOURCE
Codex Alimentarius
Codex GSFA
Codex GSFA Status
Codex Alimentarius GSFA permissions and maximum-use rows.
| Jurisdiction | INS / E-number | Function | Food category | Max level | Notes |
|---|---|---|---|---|---|
| Codex | 1100(i) | Flour treatment agent | 06.2 Flours and starches (including soybean powder) | GMP | - |
| Codex | 1100(ii) | Flour treatment agent | Table 3 Foods in General (GMP) | GMP | Table 3 additive - GMP in foods in general |
| Codex | 1100(iii) | Flour treatment agent | 06.2 Flours and starches (including soybean powder) | GMP | Excluding products conforming to the Standard for Wheat Flour (CXS 152-1985). |
| Codex | 1100(iv) | Flour treatment agent | Table 3 Foods in General (GMP) | GMP | Table 3 additive - GMP in foods in general |
| Codex | 1100(v) | Flour treatment agent | Table 3 Foods in General (GMP) | GMP | Table 3 additive - GMP in foods in general |
SOURCE
FDA
FDA GRAS
FDA GRAS Status
US FDA GRAS notice evidence from enriched and notice tables.
| Jurisdiction | GRN | Substance | FDA response | Intended use | Basis | Notifier |
|---|---|---|---|---|---|---|
| United States | 22 | alpha-Amylase derived from Bacillus licheniformis carrying a gene encoding a modified alpha-amylase derived from Bacillus lichenformis and Bacillus amyloliquefaciens | FDA has no questions | Use in the starch industry (for the liquefaction of starch in the production of syrups), and in the alcohol industry (for the thinning of starch in distilling mashes) as a... | Scientific procedures | Novo Nordisk |
| United States | 24 | alpha-Amylase derived from Bacillus licheniformis carrying a gene encoding alpha-amylase from Bacillus stearothermophilus | FDA has no questions | Use in the starch industry (for the liquefaction of starch in the production of syrups) and in the alcohol industry (for the thinning of starch in distilling mashes) as a... | Scientific procedures | Novo Nordisk |
| United States | 79 | alpha-Amylase derived from Bacillus licheniformis carrying a gene encoding a modified alpha-amylase from Bacillus licheniformis | FDA has no questions | Use as a processing aid for the liquefaction of starch in the production of syrups and for the thinning of starch in distilling mashes in the production of alcohol. The... | Scientific procedures | Novozymes North America Inc. |
| United States | 126 | alpha-Amylase enzyme preparation from Pseudomonas fluorescens Biovar I expressing a gene encoding a hybrid alpha-amylase derived from three microorganisms within the order Thermococcales | FDA has no questions | Use as an enzyme for the hydrolysis of edible starch to produce various starch hydrolysis products and to produce fermentable sugars for use in the production of distilled ethanol... | Scientific procedures | Innovase LLC |
| United States | 664 | Alpha-amylase from Cytophaga sp. expressed in Bacillus licheniformis | FDA has no questions | Intended for use as a processing aid in carbohydrate processing, to produce sugar syrups, and in fermentation to produce products such as potable alcohol and organic acids. | Scientific procedures | Dupont |
| United States | 751 | Maltogenic alpha-amylase from Bacillus stearothermophilus produced in Bacillus subtilis | FDA has no questions | For use in processing starch in food manufacturing at the minimum levels necessary to achieve the intended technical effect. | Scientific procedures | Novozymes North America, Inc. |
| United States | 842 | Maltogenic alpha-amylase | FDA has no questions | For use as an enzyme in the production of baked goods according to current good manufacturing practice (cGMP) | Scientific procedures | Mascoma LLC |
| United States | 974 | Maltogenic alpha-amylase enzyme preparation produced by Bacillus subtilis | FDA has no questions | Intended for use as an enzyme in baking and other cereal-based processes at 22 mg Total Organic Solids per kg raw material. | Scientific procedures | AB Enzymes Inc. |
| United States | 975 | Maltogenic alpha-amylase enzyme preparation produced by Bacillus licheniformis carrying the gene coding for maltogenic alpha-amylase from Geobacillus stearothermophilus | FDA has no questions | Intended for use as an enzyme at 25 milligrams Total Organic Solids (TOS) per kilogram starch-derived dry matter during processing of starch, cereals, and cereal-based beverages... | Scientific procedures | Novazymes NA |
| United States | 1011 | Alpha-amylase enzyme preparation produced by Bacillus subtilis strain AR-651 expressing the gene encoding alpha-amylase from Thermoactinomyces vulgaris | FDA has no questions | Intended for use as an enzyme at a maximum level of 100 mg total organic solids/kg flour during baking. | Scientific procedures | AB Enzymes Inc. |
| United States | 1097 | Maltogenic alpha-amylase enzyme preparation produced by Escherichia coli expressing a gene encoding a maltogenic alpha-amylase from Geobacillus stearothermophilus | FDA has no questions | Intended for use as an enzyme at up to 34 mg total organic solids (TOS)/kg raw material in baking, brewing, and starch processing. | Scientific procedures | Advanced Enzymes Technologies Ltd. |
| United States | 22 | alpha-Amylase derived from <i>Bacillus licheniformis</i> carrying a gene encoding a modified alpha-amylase derived from <i>Bacillus lichenformis</i> and <i>Bacillus amyloliquefaciens</i> | FDA has no questions | Use in the starch industry (for the liquefaction of starch in the production of syrups), and in the alcohol industry (for the thinning of starch in distilling mashes) as a... | Scientific procedures | Novo Nordisk |
| United States | 24 | alpha-Amylase derived from <i>Bacillus licheniformis</i> carrying a gene encoding alpha-amylase from <i>Bacillus stearothermophilus</i> | FDA has no questions | Use in the starch industry (for the liquefaction of starch in the production of syrups) and in the alcohol industry (for the thinning of starch in distilling mashes) as a... | Scientific procedures | Novo Nordisk |
| United States | 79 | alpha-Amylase derived from <i>Bacillus licheniformis</i> carrying a gene encoding a modified alpha-amylase from <i>Bacillus licheniformis</i> | FDA has no questions | Use as a processing aid for the liquefaction of starch in the production of syrups and for the thinning of starch in distilling mashes in the production of alcohol. The... | Scientific procedures | Novozymes North America Inc. |
| United States | 126 | alpha-Amylase enzyme preparation from <i>Pseudomonas fluorescens</i> Biovar I expressing a gene encoding a hybrid alpha-amylase derived from three microorganisms within the order <i>Thermococcales</i> | FDA has no questions | Use as an enzyme for the hydrolysis of edible starch to produce various starch hydrolysis products and to produce fermentable sugars for use in the production of distilled ethanol... | Scientific procedures | Innovase LLC |
| United States | 664 | Alpha-amylase from <I>Cytophaga</I> sp. expressed in <I>Bacillus licheniformis</I> | FDA has no questions (in PDF) | Intended for use as a processing aid in carbohydrate processing, to produce sugar syrups, and in fermentation to produce products such as potable alcohol and organic acids. | Scientific procedures | Dupont |
| United States | 842 | Maltogenic alpha-amylase | FDA has no questions (in PDF) | For use as an enzyme in the production of baked goods according to current good manufacturing practice (cGMP) | Scientific procedures | Mascoma LLC |
| United States | 974 | Maltogenic alpha-amylase enzyme preparation produced by <i>Bacillus subtilis</i> | FDA has no questions (in PDF) | Intended for use as an enzyme in baking and other cereal-based processes at 22 mg Total Organic Solids per kg raw material. | Scientific procedures | AB Enzymes Inc. |
| United States | 975 | Maltogenic alpha-amylase enzyme preparation produced by <i>Bacillus licheniformis</i> carrying the gene coding for maltogenic alpha-amylase from <i>Geobacillus stearothermophilus</i> | FDA has no questions (in PDF) | Intended for use as an enzyme at 25 milligrams Total Organic Solids (TOS) per kilogram starch-derived dry matter during processing of starch, cereals, and cereal-based beverages... | Scientific procedures | Novazymes NA |
| United States | 1011 | Alpha-amylase enzyme preparation produced by <i>Bacillus subtilis</i> strain AR-651 expressing the gene encoding alpha-amylase from <i>Thermoactinomyces vulgaris</i> | FDA has no questions (in PDF) | Intended for use as an enzyme at a maximum level of 100 mg total organic solids/kg flour during baking. | Scientific procedures | AB Enzymes Inc. |
| United States | 1097 | Maltogenic alpha-amylase enzyme preparation produced by <i>Escherichia coli</i> expressing a gene encoding a maltogenic alpha-amylase from <i>Geobacillus stearothermophilus</i> | FDA has no questions (in PDF) | Intended for use as an enzyme at up to 34 mg total organic solids (TOS)/kg raw material in baking, brewing, and starch processing. | Scientific procedures | Advanced Enzymes Technologies Ltd. |
| United States | 751 | Maltogenic alpha-amylase from <I>Bacillus stearothermophilus</I> produced in <I>Bacillus subtilis</I> | FDA has no questions (in PDF) | For use in processing starch in food manufacturing at the minimum levels necessary to achieve the intended technical effect. | Scientific procedures | Novozymes North America, Inc. |
SOURCE
JECFA
JECFA ADI
JECFA ADI Values
JECFA ADI records and evaluation years.
| Jurisdiction | Chemical name | JECFA no. | CAS | ADI | ADI upper | Function | Evaluation year |
|---|---|---|---|---|---|---|---|
| JECFA | alpha-AMYLASE from BACILLUS STEAROTHERMOPHILUS | - | 9000-85-5 (alpha-Amylase, bacterial) | NOT SPECIFIED | - | ENZYME_PREPARATION | 1990 |
| JECFA | BACILLUS MEGATERIUM alpha-AMYLASE expressed in BACILLUS SUBTILIS | - | - | no_data | - | - | 1990 |
| JECFA | BACILLUS STEAROTHERMOPHILUS alpha-AMYLASE | - | - | no_data | - | - | 1990 |
| JECFA | BACILLUS STEAROTHERMOPHILUS alpha-AMYLASE expressed in BACILLUS SUBTILIS | - | - | no_data | - | - | 1990 |
| JECFA | BACILLUS SUBTILIS alpha-AMYLASE | - | - | no_data | - | - | 1990 |
| JECFA | alpha-AMYLASE from BACILLUS STEAROTHERMOPHILUS expressed in BACILLUS SUBTILIS | - | 9000-85-5 (alpha-Amylase, bacterial) | NOT SPECIFIED | - | ENZYME_PREPARATION | 1990 |
| JECFA | alpha-AMYLASE from BACILLUS SUBTILIS | - | 9000-85-5 (alpha-Amylase, Bacterial) | NOT SPECIFIED | - | ENZYME_PREPARATION | 1990 |
| JECFA | ASPERGILLUS ORYZAE, VAR. alpha-AMYLASE and GLUCOAMYLASE | - | - | no_data | - | - | 1987 |
| JECFA | alpha-AMYLASE from BACILLUS MEGATERIUM expressed in BACILLUS SUBTILIS | - | 9000-85-5 (ALPHA-AMYLASE, BACTERIAL) | NOT SPECIFIED | - | ENZYME_PREPARATION | 1990 |
| JECFA | CARBOHYDRASE (alpha-AMYLASE) from BACILLUS LICHENIFORMIS | - | 9000-85-5 (alpha-Amylase, bacterial) | NOT SPECIFIED | - | ENZYME_PREPARATION | 1985 |
| JECFA | ASPERGILLUS ORYZAE, VAR. alpha-AMYLASE | - | - | no_data | - | - | 1987 |
| JECFA | alpha-AMYLASE from ASPERGILLUS ORYZAE, VAR. | - | 9001-19-8 (Taka-diastase) | NOT SPECIFIED | - | ENZYME_PREPARATION | 1987 |
| JECFA | alpha-AMYLASE and GLUCOAMYLASE from ASPERGILLUS ORYZAE, VAR. | - | 9000-92-4 (Amylase) | no_data | - | ENZYME_PREPARATION | 1987 |
| JECFA | alpha-AMYLASE (thermostable) from BACILLUS LICHENIFORMIS containing a modified alpha-AMYLASE gene from B. LICHENIFORMIS | - | - | NOT SPECIFIED | - | ENZYME_PREPARATION | 2003 |
| JECFA | alpha-AMYLASE (JECFA95-1) from GEOBACILLUS STEAROTHERMOPHILUS expressed in BACILLUS LICHENIFORMIS | JECFA95-1 | 9000-90-2 | NOT SPECIFIED (TEMPORARY) | - | ENZYME_PREPARATION | 2025 |
| JECFA | alpha-AMYLASE (JECFA95-2) from GEOBACILLUS STEAROTHERMOPHILUS expressed in BACILLUS LICHENIFORMIS | JECFA95-2 | 9000-90-2 | NOT SPECIFIED (TEMPORARY) | - | ENZYME_PREPARATION | 2025 |
| JECFA | alpha-AMYLASE from RHIZOMUCOR PUSILLUS expressed in ASPERGILLUS NIGER | JECFA95-3 | 9000-90-2 | NOT SPECIFIED (TEMPORARY) | - | ENZYME_PREPARATION | 2025 |
| JECFA | alpha-Amylase (JECFA95-3) from Rhizomucor pusillus expressed in Aspergillus niger | - | 9000-90-2 | NOT SPECIFIED | - | - | 2025 |
SOURCE
ingredients
ghs classifications
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
SOURCE
FAQPage JSON-LD
public food renderer rows
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is alpha-Amylase used for in food?
alpha-Amylase appears in food-use rows as: stabilizer; Flour treatment agent.
Is alpha-Amylase / E1100 safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: JECFA ADI NOT SPECIFIED. EU status evidence: Not listed as EU additive (processing aid). US/FDA evidence: FDA has no questions.
What is the ADI for alpha-Amylase?
alpha-Amylase has this ADI/reference value in the food-safety tables: JECFA ADI NOT SPECIFIED. Source: JECFA 1990.
Is alpha-Amylase also used in cosmetics?
alpha-Amylase has a same-CAS cosmetics cross-reference: Amylase, EU status permitted.