Food Safety Substance
Chitosan
Chitosan is a food additive with Novel food in the EU, At the notifier's request, FDA ceased to evaluate this notice in the US, and data from 5 regulatory sources.
CAS 9012-76-4
Indexable evidence set
FDA
At the notifier's request, FDA ceased to evaluate this notice
ADI / TDI
No ADI/TDI row found
Codex
0 row(s)
SOURCE
D1 identity resolution
e number aliases | Food Additives | dsstox identifiers | 5 matched regulatory source group(s)
Substance Identity
Resolved identifiers used to render this food-safety record.
Substance name
Chitosan
CAS
9012-76-4
DTXSID
DTXSID6030992
Evidence tier
Indexable evidence set (7)
SOURCE
EU Commission
FDA | Health Canada | Codex Alimentarius
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| European Union | EU Commission | Novel food | - |
| United States | FDA | At the notifier's request, FDA ceased to evaluate this notice | GRAS notice |
| Canada | Health Canada | Listed | Preservative |
SOURCE
FDA
FDA GRAS
FDA GRAS Status
US FDA GRAS notice evidence from enriched and notice tables.
| Jurisdiction | GRN | Substance | FDA response | Intended use | Basis | Notifier |
|---|---|---|---|---|---|---|
| United States | 73 | Shrimp-derived chitosan | At the notifier's request, FDA ceased to evaluate this notice | Use in foods in general for multiple technical effects in accordance with good manufacturing practice | Scientific procedures | Primex Ingredients ASA |
| United States | 170 | Shrimp-derived chitosan | At the notifier's request, FDA ceased to evaluate this notice | Ingredient in food including meat and poultry products | Scientific procedures | Primex ehf |
| United States | 397 | Chitosan from Aspergillus niger | FDA has no questions | As a secondary direct food ingredient in alcoholic beverage production at levels between 10 and 500 grams per hectoliter (100 liters) | Scientific procedures | KitoZyme sa |
| United States | 443 | Shrimp-derived chitosan | At the notifier's request, FDA ceased to evaluate this notice | Use in foods generally including meat and poultry, for multiple technical effects | Scientific procedures | Primex ehf |
| United States | 991 | Chitosanase enzyme preparation produced by Bacillus subtilis | FDA has no questions | Intended for use as an enzyme at up to 2.55 g Total Organic Solids (TOS)/kg chitosan in the manufacture of water-soluble chitosan. | Scientific procedures | Advanced Enzyme Technologies Ltd. |
| United States | 997 | Chitosan and beta-1,3-glucans from white button mushrooms (Agaricus bisporus) | FDA has no questions | Intended for use as an antimicrobial at levels ranging from 0.015 g to 0.15 g per 100 g of food in baked goods and mixes, alcoholic cocktail drinks, beer, cider, seltzer, wine... | Scientific procedures | Chinova Bioworks Inc. |
| United States | 73 | Shrimp-derived chitosan | At the notifier's request, FDA ceased to evaluate this notice | Use in foods in general for multiple technical effects in accordance with good manufacturing practice | Scientific procedures | Primex Ingredients ASA |
| United States | 170 | Shrimp-derived chitosan | At the notifier's request, FDA ceased to evaluate this notice | Ingredient in food including meat and poultry products | Scientific procedures | Primex ehf |
| United States | 397 | Chitosan from <i>Aspergillus niger</i> | FDA has no questions | As a secondary direct food ingredient in alcoholic beverage production at levels between 10 and 500 grams per hectoliter (100 liters) | Scientific procedures | KitoZyme sa |
| United States | 443 | Shrimp-derived chitosan | At the notifier's request, FDA ceased to evaluate this notice | Use in foods generally including meat and poultry, for multiple technical effects | Scientific procedures | Primex ehf |
| United States | 991 | Chitosanase enzyme preparation produced by <i>Bacillus subtilis</i> | FDA has no questions (in PDF) | Intended for use as an enzyme at up to 2.55 g Total Organic Solids (TOS)/kg chitosan in the manufacture of water-soluble chitosan. | Scientific procedures | Advanced Enzyme Technologies Ltd. |
| United States | 997 | Chitosan and <i>beta</i>-1,3-glucans from white button mushrooms (<i>Agaricus bisporus</i>) | FDA has no questions (in PDF) | Intended for use as an antimicrobial at levels ranging from 0.015 g to 0.15 g per 100 g of food in baked goods and mixes, alcoholic cocktail drinks, beer, cider, seltzer, wine... | Scientific procedures | Chinova Bioworks Inc. |
SOURCE
Health Canada
Health Canada Status
Health Canada food-additive permissions by functional class and food scope.
| Jurisdiction | Class | Permitted foods | Maximum level | List |
|---|---|---|---|---|
| Canada | Preservative | (a)Apricot nectar; Concentrated (naming the fruit) juice; Concentrates for unstandardized beverages containing fruit juice; Fruit-based or dairy-based smoothie beverages; Fruit-flavoured drinks; (Naming the fruit)... | (a)600 ppm | List of Permitted Preservatives |
| Canada | Preservative | (b)Bread; Unstandardized bakery products | (b)1,000 ppm | List of Permitted Preservatives |
| Canada | Preservative | (c)Caffeinated energy drinks; Unstandardized alcoholic beverages; Unstandardized fermented tea beverages; Unstandardized non-alcoholic water-based beverages; Unstandardized tea beverages; Unstandardized vegetable... | (c)400 ppm | List of Permitted Preservatives |
| Canada | Preservative | (d)Cheddar cheese; (Naming the variety) cheese; Cold-pack (naming the variety) cheese; Cold-pack cheese food; Cold-pack (naming the variety) cheese with (naming the added ingredients); Cold-pack cheese food with (naming... | (d)1,500 ppm | List of Permitted Preservatives |
| Canada | Preservative | (e)Egg-based desserts; Fruit-based desserts | (e)800 ppm | List of Permitted Preservatives |
| Canada | Preservative | (f)Fillings; Toppings; Unstandardized table syrups | (f)1,000 ppm | List of Permitted Preservatives |
| Canada | Preservative | (g)Fresh pasta; Fresh noodles | (g)200 ppm | List of Permitted Preservatives |
| Canada | Preservative | (h)Frostings; Icings | (h)400 ppm | List of Permitted Preservatives |
| Canada | Preservative | (i)Liquid plant protein isolate-based products that resemble egg products | (i)1,500 ppm | List of Permitted Preservatives |
| Canada | Preservative | (j)Liquid soup bases; Liquid soup mixes; Soups | (j)400 ppm | List of Permitted Preservatives |
| Canada | Preservative | (k)Liquid table-top sweeteners | (k)1,000 ppm | List of Permitted Preservatives |
| Canada | Preservative | (l)Meal replacement bars; Nutritional supplement bars | (l)200 ppm | List of Permitted Preservatives |
| Canada | Preservative | (m)Plant-based products that resemble cheese | (m)1,500 ppm | List of Permitted Preservatives |
| Canada | Preservative | (n)Relishes | (n)800 ppm | List of Permitted Preservatives |
| Canada | Preservative | (o)Simulated meat products; Simulated poultry products | (o)1,500 ppm | List of Permitted Preservatives |
| Canada | Preservative | (p)Unstandardized coffee beverages | (p)150 ppm | List of Permitted Preservatives |
| Canada | Preservative | (q)Unstandardized confectionery coatings | (q)1,000 ppm | List of Permitted Preservatives |
| Canada | Preservative | (r)Unstandardized fruit spreads | (r)1,000 ppm | List of Permitted Preservatives |
| Canada | Preservative | (s)Unstandardized salad dressings | (s)1,000 ppm | List of Permitted Preservatives |
| Canada | Preservative | (t)Unstandardized sauces | (t)1,000 ppm | List of Permitted Preservatives |
| Canada | Preservative | (u)Unstandardized snack bars | (u)200 ppm | List of Permitted Preservatives |
| Canada | Preservative | (v)Unstandardized vegetable purées | (v)400 ppm | List of Permitted Preservatives |
| Canada | Preservative | (w)Yogurt | (w)1,000 ppm | List of Permitted Preservatives |
SOURCE
ingredients
ghs classifications
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
SOURCE
Cross-vertical comparison
ingredients | ghs classifications
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
SOURCE
FAQPage JSON-LD
public food renderer rows
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Chitosan used for in food?
Chitosan appears in food-use rows as: Preservative; Preservative.
Is Chitosan safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. EU status evidence: Novel food. US/FDA evidence: At the notifier's request, FDA ceased to evaluate this notice.
What is the ADI for Chitosan?
No ADI row was found for Chitosan in the rendered EFSA, food_substances, food_additives, or JECFA tables.
Is Chitosan also used in cosmetics?
Chitosan has a same-CAS cosmetics cross-reference: Chitosan, EU status permitted.