NOAEL Studies Cosmetic Ingredient

1,2,4-Trihydroxybenzene NOAEL Studies

INCI: 1,2,4-TRIHYDROXYBENZENE

CAS: 533-73-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

Back to parent ingredient page
COSMOS DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 50 mg/kg bw/day rat oral 91 day Subchronic SCCP; M. Hill. IMEXINE OAM: 13 week oral toxicity study in rats with toxicokinetics. RTCResearch Toxicology Centre, Report N° 7698/T/303/2000, 2001
SCCS Opinion 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =50 mg/kg bw/day - - - NOAEL study p.16
SCCS Opinion NOAEL =1452 - - - - NOAEL study p.17
Regulatory source 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 50 mg/kg bw/day - - - - p.16
Regulatory source - 1452 - - - - - p.17
Regulatory source - 50 mg/kg bw/day rat oral 90-day - p.19
Regulatory source dermal absorption 50 mg/kg bw/day rat oral 90-day dermal absorption p.25
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 173O8B04RD UNII - - - chemical -