Moderate Cosmetic Ingredient

1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate

INCI: 1,3,4,6-TETRAMETHYL-2-PYRIMIDONE SULFATE

CAS Number
Not publicly assigned for the sulfate salt form; base pyrimidone CAS 78365-50-1 (different isomer)
Function
Hair dyeing
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically restricted by FDA; no CIR review found

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hair dye ingredient with minimal publicly available safety data; used as a sulfate salt of a pyrimidone derivative

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Concern Level: Moderate

Frequently Asked Questions

Is 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate safe in cosmetics?

Hair dye ingredient with minimal publicly available safety data; used as a sulfate salt of a pyrimidone derivative The EU classifies 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate as "permitted". Safety rating: MODERATE.

Is 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate allowed in the EU?

1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate do in cosmetics?

1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate functions as: Hair dyeing. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned for the sulfate salt form; base pyrimidone CAS 78365-50-1 (different isomer).

What is the Margin of Safety for 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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