NOAEL Studies Cosmetic Ingredient

2-Amino-5-Ethylphenol HCl NOAEL Studies

INCI: 2-AMINO-5-ETHYLPHENOL HCL

CAS: 149861-22-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCS Opinion 6 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =0.026 mg/kg bw/d rat oral 90 day dermal absorption p.26
SCCS Opinion NOAEL =7 - - oral 90 days NOAEL study p.25
SCCS Opinion NOAEL =16 mg/kg bw/day rat - Chronic genotoxicity p.17
SCCS Opinion NOAEL =16 mg/kg bw/d rat oral 90 day dermal absorption p.26
SCCS Opinion NOAEL =74 mg/kg bw/day - oral developmental developmental toxicity p.23
SCCS Opinion NOAEL =369 mg/kg bw/day - oral developmental developmental toxicity p.23
Regulatory source 9 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 7 - - oral 90 days - p.25
Regulatory source dermal absorption =0.026 mg/kg bw/d rat oral 90 day dermal absorption p.26
Regulatory source dermal absorption =16 mg/kg bw/d rat oral 90 day dermal absorption p.26
Regulatory source developmental toxicity 74 mg/kg bw/day - oral developmental developmental toxicity p.23
Regulatory source developmental toxicity 369 mg/kg bw/day - oral developmental developmental toxicity p.23
Regulatory source genotoxicity 16 mg/kg bw/day rat - Chronic genotoxicity p.17
Regulatory source repeated dose toxicity 16 mg/kg bw/day rat oral subchronic repeated dose toxicity p.27
Regulatory source repeated dose toxicity 369 mg/kg bw/day rat oral subchronic repeated dose toxicity p.27
Regulatory source reproductive toxicity 74 mg/kg bw/day mouse oral developmental reproductive toxicity p.27
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier B5IWK1V8FX UNII - - - chemical -