2-Hexyloxycarbonyl-P-Phenylenediamine HCl

INCI: 2-HEXYLOXYCARBONYL-P-PHENYLENEDIAMINE HCL

CAS Number
Not confirmed in available databases (PPD derivative; parent PPD is 106-50-3)
Function
Hair dyeing — oxidative hair dye developer/coupler
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes PPD and its derivatives reviewed by CIR — safe as hair dye ingredients at current concentrations of use; unsafe for dermal coloring (e.g., black henna tattoos)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Strong sensitizer class contraindicated outside hair dye use; FDA mandates warnings under section 601 of the FD&C Act

⚠️
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is 2-Hexyloxycarbonyl-P-Phenylenediamine HCl safe in cosmetics?

Strong sensitizer class contraindicated outside hair dye use; FDA mandates warnings under section 601 of the FD&C Act The EU classifies 2-Hexyloxycarbonyl-P-Phenylenediamine HCl as "prohibited". Safety rating: MODERATE.

Is 2-Hexyloxycarbonyl-P-Phenylenediamine HCl allowed in the EU?

2-Hexyloxycarbonyl-P-Phenylenediamine HCl EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 2-Hexyloxycarbonyl-P-Phenylenediamine HCl do in cosmetics?

2-Hexyloxycarbonyl-P-Phenylenediamine HCl functions as: Hair dyeing — oxidative hair dye developer/coupler. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in available databases (PPD derivative; parent PPD is 106-50-3).

What is the Margin of Safety for 2-Hexyloxycarbonyl-P-Phenylenediamine HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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