Acetophenone Ethyleneglycol Cyclic Acetal

INCI: ACETOPHENONE ETHYLENEGLYCOL CYCLIC ACETAL

CAS Number
Reported variously; the cyclic acetal of acetophenone with ethylene glycol is 2-methyl-2-phenyl-1,3-dioxolane — verify CAS on supplier COA (commonly cited as 936-51-6)
Function
Fragrance
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; no specific FDA/CIR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Acetals can hydrolyze under acidic conditions releasing acetophenone and ethylene glycol; verify pH stability in formulation matrix as ethylene glycol is toxic orally but not dermally at trace levels.

⚠️
Concern Level: Moderate

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Acetophenone Ethyleneglycol Cyclic Acetal safe in cosmetics?

Acetals can hydrolyze under acidic conditions releasing acetophenone and ethylene glycol; verify pH stability in formulation matrix as ethylene glycol is toxic orally but not dermally at trace levels. The EU classifies Acetophenone Ethyleneglycol Cyclic Acetal as "permitted". Safety rating: GOOD.

Is Acetophenone Ethyleneglycol Cyclic Acetal allowed in the EU?

Acetophenone Ethyleneglycol Cyclic Acetal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acetophenone Ethyleneglycol Cyclic Acetal do in cosmetics?

Acetophenone Ethyleneglycol Cyclic Acetal functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: Reported variously; the cyclic acetal of acetophenone with ethylene glycol is 2-methyl-2-phenyl-1,3-dioxolane — verify CAS on supplier COA (commonly cited as 936-51-6).

What is the Margin of Safety for Acetophenone Ethyleneglycol Cyclic Acetal?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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