Regulatory Status
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Safety Data
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Expert Verdict
Acetyl dipeptide-1 cetyl ester is a neurocosmetic active that modulates neuropeptide signaling to reduce sensory neuron firing, addressing reactive skin symptoms through CGRP and substance P pathway modulation without EU or US restrictions.
Regulatory Flags
Frequently Asked Questions
Is Acetyl Dipeptide-1 Cetyl Ester safe in cosmetics?
Acetyl dipeptide-1 cetyl ester is a neurocosmetic active that modulates neuropeptide signaling to reduce sensory neuron firing, addressing reactive skin symptoms through CGRP and substance P pathway modulation without EU or US restrictions. The EU classifies Acetyl Dipeptide-1 Cetyl Ester as "permitted". Safety rating: GOOD.
Is Acetyl Dipeptide-1 Cetyl Ester allowed in the EU?
Acetyl Dipeptide-1 Cetyl Ester EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetyl Dipeptide-1 Cetyl Ester do in cosmetics?
Acetyl Dipeptide-1 Cetyl Ester functions as: Neurotransmitter inhibitor dipeptide that stimulates nerve cells to release met-enkephalin, an endogenous opioid peptide. Results in muscle relaxation and reduced skin inflammation. Mechanism is distinct from SNARE complex inhibitors and postsynaptic receptor antagonists, enabling multi-pathway combination formulation strategies.. It is classified as a Active Ingredient in our database. CAS number: 196604-48-5.
What is the Margin of Safety for Acetyl Dipeptide-1 Cetyl Ester?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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