Acetyl Rheum Rhaponticum Root Extract

INCI: ACETYL RHEUM RHAPONTICUM ROOT EXTRACT

CAS Number
Not publicly assigned for the acetylated extract form
Function
Bleaching — lightens shade of hair or skin
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted by FDA; botanical extracts must comply with labeling requirements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains hydroxystilbenes with selective ERβ agonist activity demonstrating potent estrogenic effects in vitro; endocrine disruption potential must be assessed. As a skin-bleaching agent, monitor for hydroquinone-like effects and ensure compliance with EU restrictions on skin-lightening claims. Batch-to-batch consistency of active constituents (rhaponticin, desoxyrhaponticin, rhapontigenin) must be controlled.

⚠️
Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Acetyl Rheum Rhaponticum Root Extract safe in cosmetics?

Contains hydroxystilbenes with selective ERβ agonist activity demonstrating potent estrogenic effects in vitro; endocrine disruption potential must be assessed. As a skin-bleaching agent, monitor for hydroquinone-like effects and ensure compliance with EU restrictions on skin-lightening claims. Batch-to-batch consistency of active constituents (rhaponticin, desoxyrhaponticin, rhapontigenin) must be controlled. The EU classifies Acetyl Rheum Rhaponticum Root Extract as "permitted". Safety rating: MODERATE.

Is Acetyl Rheum Rhaponticum Root Extract allowed in the EU?

Acetyl Rheum Rhaponticum Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acetyl Rheum Rhaponticum Root Extract do in cosmetics?

Acetyl Rheum Rhaponticum Root Extract functions as: Bleaching — lightens shade of hair or skin. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned for the acetylated extract form.

What is the Margin of Safety for Acetyl Rheum Rhaponticum Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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