ACRYLAMIDE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for ACRYLAMIDE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 0.5 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
ACRYLAMIDE is listed in the EU CosIng database with functions: Not Reported It is restricted under EU Cosmetics Regulation. Restriction: II/681.
Regulatory Flags
Frequently Asked Questions
Is ACRYLAMIDE safe in cosmetics?
ACRYLAMIDE is listed in the EU CosIng database with functions: Not Reported It is restricted under EU Cosmetics Regulation. Restriction: II/681. The EU classifies ACRYLAMIDE as "Restricted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is ACRYLAMIDE allowed in the EU?
ACRYLAMIDE EU regulatory status: Restricted. Maximum allowed concentration: II/681. This is based on EU Regulation 1223/2009 and its amendments.
What does ACRYLAMIDE do in cosmetics?
ACRYLAMIDE functions as: Not Reported. It is classified as a cosmetic ingredient in our database. CAS number: 79-06-1.
What is the Margin of Safety for ACRYLAMIDE?
NOAEL: No definitive NOAEL โ EFSA 2015 opinion treats acrylamide as a genotoxic carcinogen and uses BMDL10 values (0.17โ0.43 mg/kg bw/day) rather than a NOAEL | Source: EFSA Panel on Contaminants in the Food Chain (CONTAM), Scientific opinion on acrylamide in food (... The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for ACRYLAMIDE?
The NOAEL (No Observed Adverse Effect Level) for ACRYLAMIDE is 0.5 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Is ACRYLAMIDE classified as hazardous under GHS?
ACRYLAMIDE carries a GHS signal word of "DANGER". Hazard statements: Toxic if swallowed Harmful in contact with skin or if inhaled Causes skin irritation Causes serious eye irritation May cause an allergic skin reaction May cause genetic defects May cause cancer Suspected of damaging fertility or the unborn child Causes damage to nervous system Causes damage to the nervous system through prolonged or repeated exposure. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance โ at cosmetic use concentrations, hazard thresholds may not be met.
Compliance Tools
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Related Ingredients
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