NOAEL Studies
Cosmetic Ingredient
Acrylates Crosspolymer NOAEL Studies
INCI: ACRYLATES CROSSPOLYMER
CAS: 9003-01-4
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
IARC Monographs 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| IARC Monographs | IARC carcinogenicity classification | 3 | IARC group | - | - | 1987 | IARC Monographs | - |
NTP ICE cancer 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP ICE cancer | IARC group | 3 | unitless | - | - | - | WOE; IARC Carcinogenicity | sheet=Data; excel_row=6231; Record_ID=cancer_102; Data_Type=WOE; Formulation_Name=2-?Propenoic acid, homopolymer; Mixture=Chemical; DTXSID=DTXSID50873988; Assay=IARC Carcinogenicity; Endpoint=IARC group; Response=3; Response_Unit=Unitless; URL=http://publications.iarc.fr/37; http://publications.iarc.fr/139; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID50873988 |
ECHA 3 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ECHA | NOAEL | =53 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab87e4b0a7c65d1ba981; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/22071/7/9/2?documentUUID=d13d71e3-65c5-4b1c-bf06-d17c5394d99a; YEAR=1988; ORIGINAL_YEAR=1988; STUDY_GROUP=ECHA IUCLID:15859158:M/F:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_7aa9db2604823bf075b14ffe338dd0de |
| ECHA | NOAEL | =240 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab87e4b0a7c65d1ba981; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/22071/7/9/2?documentUUID=d13d71e3-65c5-4b1c-bf06-d17c5394d99a; YEAR=1988; ORIGINAL_YEAR=1988; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855235_15856091:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_99491b4f40abb27092279eeacd9fe2c7 |
| ECHA | NOAEL | =460 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab87e4b0a7c65d1ba981; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/22071/7/9/2?documentUUID=d13d71e3-65c5-4b1c-bf06-d17c5394d99a; YEAR=1988; ORIGINAL_YEAR=1988; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855235_15856091:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_828ccedd6627116b82baf7b18c093264 |
ToxValDB GESTIS DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB GESTIS DNEL | DNEL systemic | =1.97 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634362:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_5e3861a8bf768ae0bba1d15d625d6a2f |
openFDA substances 5 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 73861X4K5F | UNII | - | - | - | polymer | - |
| openFDA substances | FDA UNII substance identifier | 9G2MAD7J6W | UNII | - | - | - | polymer | - |
| openFDA substances | FDA UNII substance identifier | A8371R0U5J | UNII | - | - | - | polymer | - |
| openFDA substances | FDA UNII substance identifier | D0I6NSZ87U | UNII | - | - | - | polymer | - |
| openFDA substances | FDA UNII substance identifier | KD3S7H73D3 | UNII | - | - | - | polymer | - |