Aframomum Melegueta Seed Extract

INCI: AFRAMOMUM MELEGUETA SEED EXTRACT

CAS Number
90320-21-1
Function
Skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific cosmetics regulation; plant historically GRAS-referenced under 21 CFR 182 for food use; no OTC monograph; regulated under general FDA cosmetics safety provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Well-tolerated botanical extract (Grains of Paradise) with documented skin conditioning, antioxidant, and anti-inflammatory activity via COX-2 inhibition (6-paradol). Listed in EU CosIng inventory with no restrictions. Multiple oral toxicity studies support safety at cosmetic use concentrations. Suitable for use as a skin conditioning active.

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Concern Level: Low

Regulatory Flags

plant-extract skin-conditioning antioxidant anti-inflammatory zingiberaceae no-cir-assessment limited-dermal-data grains-of-paradise ifra_fragrance

Frequently Asked Questions

Is Aframomum Melegueta Seed Extract safe in cosmetics?

Well-tolerated botanical extract (Grains of Paradise) with documented skin conditioning, antioxidant, and anti-inflammatory activity via COX-2 inhibition (6-paradol). Listed in EU CosIng inventory with no restrictions. Multiple oral toxicity studies support safety at cosmetic use concentrations. Suitable for use as a skin conditioning active. The EU classifies Aframomum Melegueta Seed Extract as "permitted". Safety rating: GOOD.

Is Aframomum Melegueta Seed Extract allowed in the EU?

Aframomum Melegueta Seed Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aframomum Melegueta Seed Extract do in cosmetics?

Aframomum Melegueta Seed Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 90320-21-1.

What is the Margin of Safety for Aframomum Melegueta Seed Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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