Aloe Barbadensis Leaf Extract

INCI: ALOE BARBADENSIS LEAF EXTRACT

CAS Number
85507-69-3 / 94349-62-9
Function
Skin conditioning, emollient, humectant, oral care/hygiene agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR (2007) concluded safe in cosmetic practices of use provided anthraquinone content does not exceed 50 ppm; no concentration restriction imposed by FDA; widely used GRAS-status botanical

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Aloe Barbadensis Leaf Extract is a well-characterised, widely used plant extract with a strong regulatory and clinical safety record in cosmetics. CIR Expert Panel (2007) concluded safe in current practices of use provided anthraquinone content does not exceed the industry-established 50 ppm limit. EU CosIng lists the ingredient as Permitted for use in cosmetics with no concentration restriction; functions include emollient, humectant, skin conditioning, and oral care. ECHA REACH registration confirms use in cosmetics and personal care products with no CLP hazard classification assigned to the cosmetic-grade extract. EWG Skin Deep rates decolorised/inner-leaf preparations at score 1โ€“2 (low hazard); score can be higher for non-decolorised whole-leaf products due to anthraquinone content. Minor sensitisation risk exists in predisposed individuals. No reproductive or developmental toxicity concerns at topical cosmetic use levels.

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Concern Level: Low

Regulatory Flags

plant-extract skin-conditioning humectant emollient soothing anti-inflammatory cir-assessed anthraquinone-limit-50ppm ewg-low-hazard reach-registered cosing-ref-54346

Frequently Asked Questions

Is Aloe Barbadensis Leaf Extract safe in cosmetics?

Aloe Barbadensis Leaf Extract is a well-characterised, widely used plant extract with a strong regulatory and clinical safety record in cosmetics. CIR Expert Panel (2007) concluded safe in current practices of use provided anthraquinone content does not exceed the industry-established 50 ppm limit. EU CosIng lists the ingredient as Permitted for use in cosmetics with no concentration restriction; functions include emollient, humectant, skin conditioning, and oral care. ECHA REACH registration confirms use in cosmetics and personal care products with no CLP hazard classification assigned to the cosmetic-grade extract. EWG Skin Deep rates decolorised/inner-leaf preparations at score 1โ€“2 (low hazard); score can be higher for non-decolorised whole-leaf products due to anthraquinone content. Minor sensitisation risk exists in predisposed individuals. No reproductive or developmental toxicity concerns at topical cosmetic use levels. The EU classifies Aloe Barbadensis Leaf Extract as "permitted". Safety rating: GOOD.

Is Aloe Barbadensis Leaf Extract allowed in the EU?

Aloe Barbadensis Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aloe Barbadensis Leaf Extract do in cosmetics?

Aloe Barbadensis Leaf Extract functions as: Skin conditioning, emollient, humectant, oral care/hygiene agent. It is classified as a cosmetic ingredient in our database. CAS number: 85507-69-3 / 94349-62-9.

What is the Margin of Safety for Aloe Barbadensis Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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