Amentoflavone

INCI: AMENTOFLAVONE

CAS Number
1617-53-4
Function
Antioxidant, skin lightening
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA; no CIR monograph specific to this ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potent inhibitor of CYP3A4 and CYP2C9 enzymes with limited cosmetic safety dossier; systemic exposure risk requires assessment.

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Concern Level: Moderate

Frequently Asked Questions

Is Amentoflavone safe in cosmetics?

Potent inhibitor of CYP3A4 and CYP2C9 enzymes with limited cosmetic safety dossier; systemic exposure risk requires assessment. The EU classifies Amentoflavone as "permitted". Safety rating: MODERATE.

Is Amentoflavone allowed in the EU?

Amentoflavone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Amentoflavone do in cosmetics?

Amentoflavone functions as: Antioxidant, skin lightening. It is classified as a cosmetic ingredient in our database. CAS number: 1617-53-4.

What is the Margin of Safety for Amentoflavone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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