Is Amentoflavone safe in cosmetics?
Amentoflavone has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Amentoflavone
Also known as: NSC 295677, UNII-9I1VC79L77, 3',8''-Biapigenin
INCI: AMENTOFLAVONE
Amentoflavone (CAS 1617-53-4) is a cosmetic cosmetic ingredient functioning as Antioxidant, skin lightening. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 1617-53-4 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, skin lightening
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
InChIKey
YUSWMAULDXZHPY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA; no CIR monograph specific to this ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Amentoflavone.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Bleaching agent
Expert Verdict
Expert safety assessment and concern-level summary for Amentoflavone.
Known Synonyms
NSC 295677
UNII-9I1VC79L77
3',8''-Biapigenin
Chemical Function
Antioxidant
Bleaching agent
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
AMENTOFLAVONE
ChEMBL ID
CHEMBL63354
Frequently Asked Questions
Is Amentoflavone allowed in the EU?
Amentoflavone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Amentoflavone do in cosmetics?
Amentoflavone functions as: Antioxidant, skin lightening. It is classified as a cosmetic ingredient in our database. CAS number: 1617-53-4.
Is Amentoflavone used outside cosmetics?
Amentoflavone also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Amentoflavone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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