Aminopropyltriisopropoxysilane

INCI: AMINOPROPYLTRIISOPROPOXYSILANE

CAS Number
Not confirmed in search results (likely related to CAS 39577-30-3 based on structural analogy)
Function
Binding agent / surface treatment (analogous to aminopropyl triethoxysilane — isopropoxy variant)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Listed in PCPC/INCI dictionary; no specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Aminoalkoxy silanes are corrosive and potential sensitizers in unreacted form. Read-across from CAS 919-30-2 safety data is appropriate. Require residual free silane limits on supplier CoA.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Aminopropyltriisopropoxysilane safe in cosmetics?

Aminoalkoxy silanes are corrosive and potential sensitizers in unreacted form. Read-across from CAS 919-30-2 safety data is appropriate. Require residual free silane limits on supplier CoA. The EU classifies Aminopropyltriisopropoxysilane as "permitted". Safety rating: MODERATE.

Is Aminopropyltriisopropoxysilane allowed in the EU?

Aminopropyltriisopropoxysilane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aminopropyltriisopropoxysilane do in cosmetics?

Aminopropyltriisopropoxysilane functions as: Binding agent / surface treatment (analogous to aminopropyl triethoxysilane — isopropoxy variant). It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in search results (likely related to CAS 39577-30-3 based on structural analogy).

What is the Margin of Safety for Aminopropyltriisopropoxysilane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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