Good Cosmetic Ingredient NOAEL Data

Ammonium Lauroyl Sarcosinate

INCI: AMMONIUM LAUROYL SARCOSINATE

CAS Number
68003-46-3
Function
Surfactant, cleansing, foaming, antistatic, hair conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR-assessed safe in rinse-off; leave-on use limited to 5%; not for use where N-nitroso compounds may form

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Ammonium Lauroyl Sarcosinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=2 other oral rat oral REACH
LOAEL 100 mg/kg bw/day oral rat oral REACH
NOAEL >=2 other oral - oral REACH

Expert Verdict

Ammonium Lauroyl Sarcosinate is a mild, amino acid-derived surfactant with a favorable CIR safety assessment; it is safe for rinse-off and leave-on use (up to 5%) but must not be co-formulated with nitrosating agents.

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Concern Level: Low

Regulatory Flags

surfactant mild-cleanser amino-acid-derived nitrosamine-watch

Frequently Asked Questions

Is Ammonium Lauroyl Sarcosinate safe in cosmetics?

Ammonium Lauroyl Sarcosinate is a mild, amino acid-derived surfactant with a favorable CIR safety assessment; it is safe for rinse-off and leave-on use (up to 5%) but must not be co-formulated with nitrosating agents. The EU classifies Ammonium Lauroyl Sarcosinate as "permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.

Is Ammonium Lauroyl Sarcosinate allowed in the EU?

Ammonium Lauroyl Sarcosinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ammonium Lauroyl Sarcosinate do in cosmetics?

Ammonium Lauroyl Sarcosinate functions as: Surfactant, cleansing, foaming, antistatic, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68003-46-3.

What is the Margin of Safety for Ammonium Lauroyl Sarcosinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ammonium Lauroyl Sarcosinate?

The NOAEL (No Observed Adverse Effect Level) for Ammonium Lauroyl Sarcosinate is >=2 other based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.

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