Amniotic Fluid

INCI: AMNIOTIC FLUID

CAS Number
No single CAS — biological matrix (complex mixture)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status restricted
US Notes Not specifically restricted by FDA; however, sourcing from human tissues would trigger FDA tissue-product regulations (21 CFR Part 1271)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Biosafety concern due to risk of pathogen transmission (viral, prion) if improperly sourced or sterilized; species origin verification required. If human-derived, presents major ethical and regulatory hurdles. If animal-derived, must comply with TSE/BSE certification. Practically obsolete in modern cosmetics, replaced by synthetic peptides and growth factors; not recommended for new formulations.

⚠️
Concern Level: High

Frequently Asked Questions

Is Amniotic Fluid safe in cosmetics?

Biosafety concern due to risk of pathogen transmission (viral, prion) if improperly sourced or sterilized; species origin verification required. If human-derived, presents major ethical and regulatory hurdles. If animal-derived, must comply with TSE/BSE certification. Practically obsolete in modern cosmetics, replaced by synthetic peptides and growth factors; not recommended for new formulations. The EU classifies Amniotic Fluid as "permitted". Safety rating: MODERATE.

Is Amniotic Fluid allowed in the EU?

Amniotic Fluid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Amniotic Fluid do in cosmetics?

Amniotic Fluid functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: No single CAS — biological matrix (complex mixture).

What is the Margin of Safety for Amniotic Fluid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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