Angelica Polymorpha Sinensis Root Extract

INCI: ANGELICA POLYMORPHA SINENSIS ROOT EXTRACT

CAS Number
92456-66-1
Function
Skin conditioning; antioxidant; anti-inflammatory; skin brightening
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. Furanocoumarin sum โ‰ค1 mg/kg in finished product (EU Regulation 1223/2009, Annex II entry 358)
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No CIR safety assessment published for this ingredient. Used as a cosmetic ingredient under general safe-use framework. Contains furanocoumarins (psoralen, bergapten, xanthotoxin, imperatorin) with known phototoxic potential at higher concentrations. EWG Skin Deep: ALL LOW hazard scores (Cancer LOW, Allergies & Immunotoxicity LOW, Dev/Repro Toxicity LOW, Use Restrictions LOW); data availability rated FAIR.

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Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Safe for cosmetic use at standard concentrations. Well-tolerated skin-conditioning, antioxidant, and anti-inflammatory ingredient with a long history of traditional use (Dong Quai/TCM). Primary consideration is furanocoumarin-mediated phototoxicity, managed by EU regulatory limits (โ‰ค1 mg/kg total furanocoumarins in finished product). EWG hazard score: all LOW categories with FAIR data. No banned or restricted status in EU or US. Suitable for general rinse-off and leave-on formulations when furanocoumarin levels are controlled; caution advised in high-concentration leave-on sun-exposed products.

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Concern Level: Low

Regulatory Flags

phototoxicity-risk-furanocoumarins sun-exposure-caution ewg-verified-restricted no-cir-assessment traditional-tcm-use antioxidant anti-inflammatory skin-brightening furanocoumarin-limit-eu

Frequently Asked Questions

Is Angelica Polymorpha Sinensis Root Extract safe in cosmetics?

Safe for cosmetic use at standard concentrations. Well-tolerated skin-conditioning, antioxidant, and anti-inflammatory ingredient with a long history of traditional use (Dong Quai/TCM). Primary consideration is furanocoumarin-mediated phototoxicity, managed by EU regulatory limits (โ‰ค1 mg/kg total furanocoumarins in finished product). EWG hazard score: all LOW categories with FAIR data. No banned or restricted status in EU or US. Suitable for general rinse-off and leave-on formulations when furanocoumarin levels are controlled; caution advised in high-concentration leave-on sun-exposed products. The EU classifies Angelica Polymorpha Sinensis Root Extract as "permitted". Safety rating: GOOD.

Is Angelica Polymorpha Sinensis Root Extract allowed in the EU?

Angelica Polymorpha Sinensis Root Extract EU regulatory status: permitted. Maximum allowed concentration: Furanocoumarin sum โ‰ค1 mg/kg in finished product (EU Regulation 1223/2009, Annex II entry 358). This is based on EU Regulation 1223/2009 and its amendments.

What does Angelica Polymorpha Sinensis Root Extract do in cosmetics?

Angelica Polymorpha Sinensis Root Extract functions as: Skin conditioning; antioxidant; anti-inflammatory; skin brightening. It is classified as a cosmetic ingredient in our database. CAS number: 92456-66-1.

What is the Margin of Safety for Angelica Polymorpha Sinensis Root Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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