Apium Graveolens Callus Extract

INCI: APIUM GRAVEOLENS CALLUS EXTRACT

CAS Number
No specific CAS (general celery extract CAS 89997-35-3 may apply)
Function
Skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted; no CIR monograph specific to callus culture

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Celery allergen cross-reactivity (celery-birch-mugwort-spice syndrome) possible; callus cultures reduce this risk. Document in PIF and confirm absence of furanocoumarins via analytical testing.

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Apium Graveolens Callus Extract safe in cosmetics?

Celery allergen cross-reactivity (celery-birch-mugwort-spice syndrome) possible; callus cultures reduce this risk. Document in PIF and confirm absence of furanocoumarins via analytical testing. The EU classifies Apium Graveolens Callus Extract as "permitted". Safety rating: GOOD.

Is Apium Graveolens Callus Extract allowed in the EU?

Apium Graveolens Callus Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Apium Graveolens Callus Extract do in cosmetics?

Apium Graveolens Callus Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: No specific CAS (general celery extract CAS 89997-35-3 may apply).

What is the Margin of Safety for Apium Graveolens Callus Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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