Arbutinyl Undecylenate

INCI: ARBUTINYL UNDECYLENATE

CAS Number
None assigned
Function
Antimicrobial, Antioxidant, Bleaching (skin lightening)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 2%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA-specific restriction on arbutin derivatives. However, hydroquinone (the metabolite) is regulated under OTC drug monograph at โ‰ค2% for skin lightening.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

SCCS concluded in SCCS/1642/22 that without data on hydroquinone release and its ultimate destination, it is not possible to determine the safe concentration of any arbutin in cosmetics. The undecylenate ester may have different hydroquinone release kinetics than alpha or beta-arbutin. While Arbutinyl Undecylenate is not explicitly listed in Annex II or III, the regulatory trajectory of arbutin-class ingredients suggests caution pending further safety data on metabolite release.

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Concern Level: High

Frequently Asked Questions

Is Arbutinyl Undecylenate safe in cosmetics?

SCCS concluded in SCCS/1642/22 that without data on hydroquinone release and its ultimate destination, it is not possible to determine the safe concentration of any arbutin in cosmetics. The undecylenate ester may have different hydroquinone release kinetics than alpha or beta-arbutin. While Arbutinyl Undecylenate is not explicitly listed in Annex II or III, the regulatory trajectory of arbutin-class ingredients suggests caution pending further safety data on metabolite release. The EU classifies Arbutinyl Undecylenate as "permitted". Safety rating: MODERATE.

Is Arbutinyl Undecylenate allowed in the EU?

Arbutinyl Undecylenate EU regulatory status: permitted. Maximum allowed concentration: 2%. This is based on EU Regulation 1223/2009 and its amendments.

What does Arbutinyl Undecylenate do in cosmetics?

Arbutinyl Undecylenate functions as: Antimicrobial, Antioxidant, Bleaching (skin lightening). It is classified as a cosmetic ingredient in our database. CAS number: None assigned.

What is the Margin of Safety for Arbutinyl Undecylenate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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