Arbutus Unedo Leaf Cell Extract

INCI: ARBUTUS UNEDO LEAF CELL EXTRACT

CAS Number
Not specifically assigned (plant cell culture derivative)
Function
Skin conditioning, antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA-specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Arbutus unedo leaves contain higher arbutin concentrations than fruit; cell culture extracts may produce arbutin depending on culture conditions and require analytical characterization. Apply hydroquinone-release logic per SCCS/1642/22.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Arbutus Unedo Leaf Cell Extract safe in cosmetics?

Arbutus unedo leaves contain higher arbutin concentrations than fruit; cell culture extracts may produce arbutin depending on culture conditions and require analytical characterization. Apply hydroquinone-release logic per SCCS/1642/22. The EU classifies Arbutus Unedo Leaf Cell Extract as "permitted". Safety rating: MODERATE.

Is Arbutus Unedo Leaf Cell Extract allowed in the EU?

Arbutus Unedo Leaf Cell Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Arbutus Unedo Leaf Cell Extract do in cosmetics?

Arbutus Unedo Leaf Cell Extract functions as: Skin conditioning, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (plant cell culture derivative).

What is the Margin of Safety for Arbutus Unedo Leaf Cell Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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