Arbutus Unedo Leaf Extract

INCI: ARBUTUS UNEDO LEAF EXTRACT

CAS Number
89957-49-3 (general *Arbutus unedo* extract CAS)
Function
Skin Conditioning, Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA-specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Arbutus unedo leaf extract has highest arbutin content risk in this group; arbutin is restricted under EU Reg. 2024/996 Annex III. Quantify arbutin content, assess HQ contamination to less than 1 ppm per SCCS guidance, and document HQ release kinetics before use.

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Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Arbutus Unedo Leaf Extract safe in cosmetics?

Arbutus unedo leaf extract has highest arbutin content risk in this group; arbutin is restricted under EU Reg. 2024/996 Annex III. Quantify arbutin content, assess HQ contamination to less than 1 ppm per SCCS guidance, and document HQ release kinetics before use. The EU classifies Arbutus Unedo Leaf Extract as "permitted". Safety rating: MODERATE.

Is Arbutus Unedo Leaf Extract allowed in the EU?

Arbutus Unedo Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Arbutus Unedo Leaf Extract do in cosmetics?

Arbutus Unedo Leaf Extract functions as: Skin Conditioning, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 89957-49-3 (general *Arbutus unedo* extract CAS).

What is the Margin of Safety for Arbutus Unedo Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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