Regulatory Status
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Safety Data
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Expert Verdict
Arctigenin exhibits potent biological activity including NF-κB inhibition, anti-proliferative, and STAT3 inhibition effects, which raises safety concern at higher concentrations. Insufficient cosmetic safety data exists; use at low concentrations until formal safety assessment is available.
Frequently Asked Questions
Is Arctigenin safe in cosmetics?
Arctigenin exhibits potent biological activity including NF-κB inhibition, anti-proliferative, and STAT3 inhibition effects, which raises safety concern at higher concentrations. Insufficient cosmetic safety data exists; use at low concentrations until formal safety assessment is available. The EU classifies Arctigenin as "permitted". Safety rating: MODERATE.
Is Arctigenin allowed in the EU?
Arctigenin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Arctigenin do in cosmetics?
Arctigenin functions as: Skin Conditioning; antioxidant, anti-inflammatory, and skin-lightening activity. It is classified as a cosmetic ingredient in our database. CAS number: 7770-78-7.
What is the Margin of Safety for Arctigenin?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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