Arctostaphylos Uva-Ursi Leaf Extract

INCI: ARCTOSTAPHYLOS UVA-URSI LEAF EXTRACT

CAS Number
84776-10-3
Function
Skin conditioning, antioxidant, skin brightening, antimicrobial
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 7%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No dedicated CIR monograph for the whole extract; arbutin (the key active) not separately assessed by CIR; hydroquinone (potential hydrolysis product) assessed by CIR as unsafe in leave-on cosmetics; FDA does not restrict arbutin or bearberry extract by name.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Safe at typical cosmetic concentrations when beta-arbutin content is controlled per EU Regulation 2024/996 (max 7% in face creams) and hydroquinone impurity remains at unavoidable trace levels; SCCS OPINION/1642/22 supports safety; endocrine disruption flagged as theoretical concern at high exposure driving the EU restriction; well-established skin brightening and antioxidant ingredient with long history of use.

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Concern Level: Low

Regulatory Flags

plant_extract arbutin_source skin_brightening tyrosinase_inhibitor eu_restricted_2024 hydroquinone_precursor_risk endocrine_disruption_concern ericaceae_family antioxidant antimicrobial leave_on_caution

Frequently Asked Questions

Is Arctostaphylos Uva-Ursi Leaf Extract safe in cosmetics?

Safe at typical cosmetic concentrations when beta-arbutin content is controlled per EU Regulation 2024/996 (max 7% in face creams) and hydroquinone impurity remains at unavoidable trace levels; SCCS OPINION/1642/22 supports safety; endocrine disruption flagged as theoretical concern at high exposure driving the EU restriction; well-established skin brightening and antioxidant ingredient with long history of use. The EU classifies Arctostaphylos Uva-Ursi Leaf Extract as "restricted". Safety rating: GOOD.

Is Arctostaphylos Uva-Ursi Leaf Extract allowed in the EU?

Arctostaphylos Uva-Ursi Leaf Extract EU regulatory status: restricted. Maximum allowed concentration: 7%. This is based on EU Regulation 1223/2009 and its amendments.

What does Arctostaphylos Uva-Ursi Leaf Extract do in cosmetics?

Arctostaphylos Uva-Ursi Leaf Extract functions as: Skin conditioning, antioxidant, skin brightening, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 84776-10-3.

What is the Margin of Safety for Arctostaphylos Uva-Ursi Leaf Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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