Argemone Mexicana Callus Extract

INCI: ARGEMONE MEXICANA CALLUS EXTRACT

Function
Antioxidant, Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA restriction; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Argemone mexicana callus extract is designed to avoid toxic alkaloids present in wild plant material, but batch-by-batch alkaloid profiling is essential to confirm absence of sanguinarine and dihydrosanguinarine. May cause mild stinging on compromised skin and eye irritation if product migrates.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Argemone Mexicana Callus Extract safe in cosmetics?

Argemone mexicana callus extract is designed to avoid toxic alkaloids present in wild plant material, but batch-by-batch alkaloid profiling is essential to confirm absence of sanguinarine and dihydrosanguinarine. May cause mild stinging on compromised skin and eye irritation if product migrates. The EU classifies Argemone Mexicana Callus Extract as "permitted". Safety rating: MODERATE.

Is Argemone Mexicana Callus Extract allowed in the EU?

Argemone Mexicana Callus Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Argemone Mexicana Callus Extract do in cosmetics?

Argemone Mexicana Callus Extract functions as: Antioxidant, Skin conditioning. It is classified as a cosmetic ingredient in our database.

What is the Margin of Safety for Argemone Mexicana Callus Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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