Asarum Heterotropoides Extract

INCI: ASARUM HETEROTROPOIDES EXTRACT

CAS Number
90045-27-3
Function
Anti-seborrheic, Antimicrobial, Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically prohibited or restricted; allowed under general provisions, but aristolochic acid content raises safety flags

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical - Contains aristolochic acid analogues (AAAs) including AA I, which are nephrotoxic and carcinogenic. A 2024 study found AA I in 60% of Asarum-containing products (0.03-0.79 ppm), and AAAs were detected in all plant parts. Exhibits hair growth-promoting activity and antiviral properties against human papillomavirus in preclinical studies; essential oil shows activity against body odor-producing bacteria

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Concern Level: High

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Asarum Heterotropoides Extract safe in cosmetics?

Critical - Contains aristolochic acid analogues (AAAs) including AA I, which are nephrotoxic and carcinogenic. A 2024 study found AA I in 60% of Asarum-containing products (0.03-0.79 ppm), and AAAs were detected in all plant parts. Exhibits hair growth-promoting activity and antiviral properties against human papillomavirus in preclinical studies; essential oil shows activity against body odor-producing bacteria The EU classifies Asarum Heterotropoides Extract as "prohibited". Safety rating: MODERATE.

Is Asarum Heterotropoides Extract allowed in the EU?

Asarum Heterotropoides Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Asarum Heterotropoides Extract do in cosmetics?

Asarum Heterotropoides Extract functions as: Anti-seborrheic, Antimicrobial, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 90045-27-3.

What is the Margin of Safety for Asarum Heterotropoides Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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