Avenacosides

INCI: AVENACOSIDES (GROUP DESIGNATION FOR STEROIDAL SAPONINS FROM OATS)

CAS Number
Avenacoside A: 26499-65-0; Avenacoside B: 35920-91-3
Function
Skin conditioning; the saponins have surface-active, anti-inflammatory, and antioxidant properties
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted; assessed as part of the CIR review of Avena sativa-derived ingredients

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Saponins at high concentrations may cause irritation due to their surfactant nature; overall safety covered under the CIR Panel assessment of oat-derived ingredients. No major standalone toxicity flags.. Steroidal saponins naturally present in oat plants; exhibit anti-inflammatory and antifungal activity; contribute to the foaming and emulsifying characteristics of oat extracts

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Concern Level: High

Frequently Asked Questions

Is Avenacosides safe in cosmetics?

Saponins at high concentrations may cause irritation due to their surfactant nature; overall safety covered under the CIR Panel assessment of oat-derived ingredients. No major standalone toxicity flags.. Steroidal saponins naturally present in oat plants; exhibit anti-inflammatory and antifungal activity; contribute to the foaming and emulsifying characteristics of oat extracts The EU classifies Avenacosides as "permitted". Safety rating: MODERATE.

Is Avenacosides allowed in the EU?

Avenacosides EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Avenacosides do in cosmetics?

Avenacosides functions as: Skin conditioning; the saponins have surface-active, anti-inflammatory, and antioxidant properties. It is classified as a cosmetic ingredient in our database. CAS number: Avenacoside A: 26499-65-0; Avenacoside B: 35920-91-3.

What is the Margin of Safety for Avenacosides?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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