Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Strong odor may limit use levels; potential for irritation at high concentrations; high in sulfur compounds (characteristic pungent smell); patch testing recommended; leaf fractions contain lower azadirachtin levels than seed fractions. Essential oil obtained from neem leaves; antibacterial, antifungal, and anti-inflammatory properties; significantly different chemical profile from neem seed oil - lower limonoid content which is why leaf derivatives have been treated differently from seed der...
Regulatory Flags
Frequently Asked Questions
Is Azadirachta Indica Leaf Oil safe in cosmetics?
Strong odor may limit use levels; potential for irritation at high concentrations; high in sulfur compounds (characteristic pungent smell); patch testing recommended; leaf fractions contain lower azadirachtin levels than seed fractions. Essential oil obtained from neem leaves; antibacterial, antifungal, and anti-inflammatory properties; significantly different chemical profile from neem seed oil - lower limonoid content which is why leaf derivatives have been treated differently from seed der... The EU classifies Azadirachta Indica Leaf Oil as "prohibited". Safety rating: MODERATE.
Is Azadirachta Indica Leaf Oil allowed in the EU?
Azadirachta Indica Leaf Oil EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Azadirachta Indica Leaf Oil do in cosmetics?
Azadirachta Indica Leaf Oil functions as: Skin conditioning, antimicrobial, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: Several avocado oil ester derivatives (\#1-4, \#6) lack discrete CAS numbers because they are complex mixtures from transesterification - this is normal for these ingredient classes and should not impede regulatory filings. <span style="display:none"></span>.
What is the Margin of Safety for Azadirachta Indica Leaf Oil?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Azadirachta Indica Leaf Oil compliance across multiple jurisdictions:
Related Ingredients
Is Azadirachta Indica Leaf Oil in Your Products?
Scan any product label with Piro โ our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free โAnalyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Azadirachta Indica Leaf Oil in your formulation.